Overexpression of BPIFB4 Alleviates COPD Inflammatory Damage by Inhibiting M1 Macrophage Activation via the PI3K/AKT Pathway
BPIFB4 overexpression alleviates M1 macrophage polarization by activating the PI3K-AKT1 pathway, thereby reducing lung tissue damage and dysfunction in COPD mice.
Authors
- Liang Gao (ORCID: https://orcid.org/0000-0001-5731-8616)
- Lili Xue (ORCID: https://orcid.org/0000-0001-8738-143X)
- Ayiguli Alimu
- Zulipikaer Abudureheman (ORCID: https://orcid.org/0000-0002-2122-0008)
- Aifang Zheng
- Chengxin Xie
- Li Li (ORCID: https://orcid.org/0000-0002-4304-0999)
- Yun Chen (ORCID: https://orcid.org/0000-0002-2146-6008)
- Hui Gong (ORCID: https://orcid.org/0000-0002-3521-2316)
- Jingran Xu (ORCID: https://orcid.org/0000-0002-8182-3927)
- Xiuqi Lu
Institutions
- Shihezi University (CN)
- Xinjiang Medical University (CN)
Publication Details
- Journal
- Lung
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1007/s00408-025-00824-4
- Citations
- 1
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- National Natural Science Foundation of China