Verbascoside restores gastrointestinal integrity and attenuates inflammation in a rat model of 5-FU-induced mucositis
The findings strongly suggest that VER offers significant protection, and these results warrant further investigation into its potential clinical application as an adjunct therapy to mitigate gastrointestinal and other toxicities associated with 5-FU chemotherapy.
Authors
- Ugochukwu Chukwunyere (ORCID: https://orcid.org/0000-0003-1280-6725)
- Ahmet Özer Şehirli (ORCID: https://orcid.org/0000-0002-5175-9290)
- İhsan Çalış (ORCID: https://orcid.org/0000-0001-5489-3420)
- Serkan Sayıner (ORCID: https://orcid.org/0000-0002-3297-5369)
- Şule Çetınel (ORCID: https://orcid.org/0000-0003-1912-3679)
- Merve Mercan
Institutions
- Near East University (CY)
- Girne American University (CY)
- Marmara University (TR)
Publication Details
- Journal
- Medical Oncology
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1007/s12032-025-02823-0
- Primary Topic
- Oral health in cancer treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00