Paraptosis-related classification and risk signature for prognosis prediction and immunotherapy assessment in gastric cancer

This study underscores the link between paraptosis subtypes and changes in the gastric cancer immunotumour microenvironment. We developed and validated the Paraptosis-Related Risk Score (PRRS), which effectively predicts survival, immune infiltration, and drug sensitivity in gastric cancer patients. Our findings enhance the understanding of paraptosis and suggest potential new therapeutic strategies for gastric cancer.

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Publication Details

Journal
Discover Oncology
Published
2025-06-16
DOI
https://doi.org/10.1007/s12672-025-02996-0
Citations
1
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
1.05
Controls
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article

Paraptosis-related classification and risk signature for prognosis prediction and immunotherapy assessment in gastric cancer

Kai Zhou, Ruyue Chen
1 citations
Discover Oncology
Cancer Immunotherapy and Biomarkers
1.05
article

Paraptosis-related classification and risk signature for prognosis prediction and immunotherapy assessment in gastric cancer

Kai Zhou, Ruyue Chen
article en
1 citations

Abstract

This study underscores the link between paraptosis subtypes and changes in the gastric cancer immunotumour microenvironment. We developed and validated the Paraptosis-Related Risk Score (PRRS), which effectively predicts survival, immune infiltration, and drug sensitivity in gastric cancer patients. Our findings enhance the understanding of paraptosis and suggest potential new therapeutic strategies for gastric cancer.

Discover OncologyVol. 16(1)
Qingdao University (CN), Affiliated Hospital of Taishan Medical University (CN), Shandong First Medical University (CN)
Good health and well-being
Openalex Percentile: Top 21%
Cancer Immunotherapy and Biomarkers
1.05
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