Paraptosis-related classification and risk signature for prognosis prediction and immunotherapy assessment in gastric cancer
This study underscores the link between paraptosis subtypes and changes in the gastric cancer immunotumour microenvironment. We developed and validated the Paraptosis-Related Risk Score (PRRS), which effectively predicts survival, immune infiltration, and drug sensitivity in gastric cancer patients. Our findings enhance the understanding of paraptosis and suggest potential new therapeutic strategies for gastric cancer.
Authors
- Kai Zhou (ORCID: https://orcid.org/0000-0002-8109-6408)
- Ruyue Chen (ORCID: https://orcid.org/0000-0002-0847-4740)
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Taishan Medical University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1007/s12672-025-02996-0
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05