Incidental Detection of Poorly Differentiated Neuroendocrine Carcinoma in Penile Urethra on 18F-Fluciclovine PET/CT

We report the case of an 88-year-old man with suspected biochemical recurrence of prostate cancer, in whom 18 F-fluciclovine PET/CT was performed in the context of rising prostate-specific antigen (PSA) levels. Incidental identification of penile urethral activity was observed. A subsequent urethral biopsy revealed a treatment-related, poorly differentiated neuroendocrine carcinoma of prostatic origin, with metastasis to the penile urethra.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2025-06-16
DOI
https://doi.org/10.1097/rlu.0000000000006028
Primary Topic
Urologic and reproductive health conditions
Type
article
Field-Weighted Citation Impact
0.00
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article

Incidental Detection of Poorly Differentiated Neuroendocrine Carcinoma in Penile Urethra on 18F-Fluciclovine PET/CT

Lien-Yen Wang, Shih‐Hao Wang, Hung‐Jen Shih, Chia-Ying Li et al.
Clinical Nuclear Medicine
Urologic and reproductive health conditions
article

Incidental Detection of Poorly Differentiated Neuroendocrine Carcinoma in Penile Urethra on 18F-Fluciclovine PET/CT

Lien-Yen Wang, Shih‐Hao Wang, Hung‐Jen Shih, Chia-Ying Li, Chun-Yi Lin
article en

Abstract

We report the case of an 88-year-old man with suspected biochemical recurrence of prostate cancer, in whom 18 F-fluciclovine PET/CT was performed in the context of rising prostate-specific antigen (PSA) levels. Incidental identification of penile urethral activity was observed. A subsequent urethral biopsy revealed a treatment-related, poorly differentiated neuroendocrine carcinoma of prostatic origin, with metastasis to the penile urethra.

Clinical Nuclear MedicineVol. 50(12)
National Chung Hsing University (TW), Changhua Christian Hospital (TW), Taipei Medical University (TW)
Good health and well-being
Openalex Percentile: Top 79%
Urologic and reproductive health conditions
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