Investigating the dynamics of intracranial pressure and cerebral autoregulation during extracorporeal cardiopulmonary resuscitation using a porcine model
This study highlights the complex intracranial changes during ECPR, emphasizing the importance of pulsatility in maintaining cerebral autoregulation. Findings suggest the need for refined ECPR protocols to optimize cerebral protection and improve autoregulatory recovery.
Authors
- Glenn J. R. Whitman (ORCID: https://orcid.org/0000-0003-3225-2360)
- Debraj Mukherjee (ORCID: https://orcid.org/0000-0002-5403-8237)
- Jessica Blair Briscoe (ORCID: https://orcid.org/0000-0003-3308-4215)
- Tania B. Porras
- Zachary Darby (ORCID: https://orcid.org/0000-0002-5906-0396)
- Anastasios Bezerianos (ORCID: https://orcid.org/0000-0002-8199-6000)
- Ifeanyi Chinedozi (ORCID: https://orcid.org/0000-0001-7012-5931)
- Nitish V. Thakor (ORCID: https://orcid.org/0000-0002-9981-9395)
- Jin Kook Kang (ORCID: https://orcid.org/0000-0003-3631-2789)
- Shivalika Khanduja (ORCID: https://orcid.org/0000-0001-5359-8075)
- Sung Min Cho (ORCID: https://orcid.org/0000-0002-7593-4815)
- Mingfeng Cao (ORCID: https://orcid.org/0009-0009-5967-584X)
- Steve Keller
Institutions
- Barrow Neurological Institute (US)
- Johns Hopkins University (US)
- Georgetown University (US)
- Johns Hopkins Medicine (US)
- MedStar Georgetown University Hospital (US)
Publication Details
- Journal
- Resuscitation Plus
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1016/j.resplu.2025.101003
- Primary Topic
- Cardiac Arrest and Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00