A comparative study of 5-aminolevulinic acid photodynamic therapy and loop electrosurgical excision procedure in the treatment of cervical high grade squamous intraepithelial lesions
5-ALA-PDT and LEEP exhibit potential similarity in efficacy in the treatment of cervical HSIL, but the former has milder adverse reactions. The involvement of the endocervical canal is a significant risk factor for both 5-ALA-PDT failure and persistent HPV infection.
Authors
- Junlei Lu
- Huan Shi (ORCID: https://orcid.org/0000-0002-7520-8776)
- Jie Yu (ORCID: https://orcid.org/0000-0001-6019-9646)
- Yingling Zheng
- Jing Qian (ORCID: https://orcid.org/0000-0002-1229-8946)
- Hongkai Shang (ORCID: https://orcid.org/0009-0005-2277-4597)
Institutions
- Zhejiang Chinese Medical University (CN)
- Westlake University (CN)
- Affiliated Hangzhou First People's Hospital, Westlake University, School of Medicine (CN)
Publication Details
- Journal
- Lasers in Medical Science
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1007/s10103-025-04537-1
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00