The Effect of Vitamin C Administration on Hemoglobin and Hematocrit of Albino Rats (Rattus norvegicus)

Anemia, a condition characterized by low hemoglobin or red blood cell levels, is a widespread nutritional issue affecting over 2 billion people globally. Iron deficiency, folic acid, and vitamin B12 or C deficiencies are common causes, with vitamin C playing a crucial role in enhancing iron absorption. This study aimed to investigate the impact of various doses of vitamin C supplementation on hematocrit and hemoglobin levels in rats. The experiment employed a True Experimental design with a control group and three treatment groups receiving different doses of vitamin C (1 mg/ml, 3 mg/ml, and 6 mg/ml) over three weeks. Results showed no significant increase in hemoglobin or hematocrit levels across treatment groups compared to the control. Although some variations were observed in the data, particularly with the 6 mg/ml dose showing a slight decrease in hemoglobin levels, the overall effect of vitamin C on these hematological parameters was not substantial. These findings suggest that animal health, feed quality, and vitamin C administration duration influence the outcomes.

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Journal
Journal of Basic Medical Veterinary
Published
2025-06-11
DOI
https://doi.org/10.20473/jbmv.v14i1.67028
Primary Topic
Diverse Scientific Research Studies
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article
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article

The Effect of Vitamin C Administration on Hemoglobin and Hematocrit of Albino Rats (Rattus norvegicus)

Ratna Damayanti, Hasna Firdhausia, Khansa Kha, Shela Syafira et al.
Journal of Basic Medical Veterinary
Diverse Scientific Research Studies
article

The Effect of Vitamin C Administration on Hemoglobin and Hematocrit of Albino Rats (Rattus norvegicus)

Ratna Damayanti, Hasna Firdhausia, Khansa Kha, Shela Syafira, Alifian Alfarizi, Annisa Cahya Reza Pahlevi, Deninda Ainaya, Naila Nisrina
article en

Abstract

Anemia, a condition characterized by low hemoglobin or red blood cell levels, is a widespread nutritional issue affecting over 2 billion people globally. Iron deficiency, folic acid, and vitamin B12 or C deficiencies are common causes, with vitamin C playing a crucial role in enhancing iron absorption. This study aimed to investigate the impact of various doses of vitamin C supplementation on hematocrit and hemoglobin levels in rats. The experiment employed a True Experimental design with a control group and three treatment groups receiving different doses of vitamin C (1 mg/ml, 3 mg/ml, and 6 mg/ml) over three weeks. Results showed no significant increase in hemoglobin or hematocrit levels across treatment groups compared to the control. Although some variations were observed in the data, particularly with the 6 mg/ml dose showing a slight decrease in hemoglobin levels, the overall effect of vitamin C on these hematological parameters was not substantial. These findings suggest that animal health, feed quality, and vitamin C administration duration influence the outcomes.

Journal of Basic Medical VeterinaryVol. 14(1)
Universitas Airlangga (ID)
Openalex Percentile: Top 77%
Diverse Scientific Research Studies
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The Effect of Vitamin C Administration on Hemoglobin and Hematocrit of Albino Rats (Rattus norvegicus) — Ratna Damayanti, Hasna Firdhausia, et al. · Journal of Basic Medical Veterinary (2025) | TGRS Research Map | TGRS