Assessing the frequency and accuracy of morphologic changes of focal bone lesions on [68Ga]Ga-PSMA-11 PET/CT in prostate cancer
Focal [<sup>68</sup>Ga]Ga-PSMA-11 positive lesions without MC on CT are frequent, especially on scans for BCR, with the majority being malignant. Considering PSMA-RADS 4 lesions on [<sup>68</sup>Ga]Ga-PSMA-11 on staging exams, significantly improves the accuracy. Incorporating clinical information and considering PSMA-RADS 3B can further improve the sensitivity for BCR scans.
Authors
- Jakob Heimer (ORCID: https://orcid.org/0000-0003-3499-8801)
- Stephan Skawran (ORCID: https://orcid.org/0000-0003-2721-9726)
- Thibika Sivakumar (ORCID: https://orcid.org/0000-0002-4228-1950)
- Irene A. Burger (ORCID: https://orcid.org/0000-0001-8029-8692)
- Martin William Huellner (ORCID: https://orcid.org/0000-0002-4849-3292)
- Daniel Eberli (ORCID: https://orcid.org/0000-0001-8866-8010)
- Urs J. Muehlematter (ORCID: https://orcid.org/0000-0003-3423-4633)
- Alexander Maurer (ORCID: https://orcid.org/0000-0002-6964-802X)
- Michael Messerli (ORCID: https://orcid.org/0000-0001-7815-3048)
- Noel Spielhofer
Institutions
- University of Zurich (CH)
- ETH Zurich (CH)
- University Hospital of Zurich (CH)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1007/s00259-025-07331-x
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universität Zürich