Evaluating the Role of Neurogenic Locus Notch Homolog Protein 1 in Oral Cancer Progression and Therapeutic Opportunities
The research demonstrated that NOTCH1 showed significant upregulation in oral squamous cell carcinoma and was associated with both immune suppression and unfavorable clinical outcomes. The investigation indicated that NOTCH1 stood as an effective biomarker and therapeutic target for oral cancer.
Authors
- Mostafa Ahmed Abdellah Ahmed
- Sajid Ali Majeedano
- N.U. Rashid
- Asma Ali
- Shah Mv
- Madeeha Minhas
- Tayyaba Rafiq
- Seemi Tanvir
Institutions
- King Saud bin Abdulaziz University for Health Sciences (SA)
Publication Details
- Journal
- Cureus
- Published
- 2025-06-16
- DOI
- https://doi.org/10.7759/cureus.86149
- Primary Topic
- Histone Deacetylase Inhibitors Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00