Magnetic Resonance Image-Guided Focused Ultrasound Ventral Intermediate Nucleus Thalamotomy with Indwelling Globus Pallidus Internus Deep Brain Stimulation Electrodes: A Case Report

This is the first report of MRgFUS thalamotomy for recurrent tremor with indwelling DBS electrodes. We found that MRgFUS thalamotomy as salvage therapy with implanted GPi DBS electrodes is both safe and effective. It represents a novel potential treatment paradigm for TdPD patients with persistent tremor despite otherwise effective GPi DBS.

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Publication Details

Journal
Stereotactic and Functional Neurosurgery
Published
2025-06-16
DOI
https://doi.org/10.1159/000546737
Primary Topic
Neurological disorders and treatments
Type
article
Field-Weighted Citation Impact
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article

Magnetic Resonance Image-Guided Focused Ultrasound Ventral Intermediate Nucleus Thalamotomy with Indwelling Globus Pallidus Internus Deep Brain Stimulation Electrodes: A Case Report

G. Rees Cosgrove, Albert Y. Hung, Nathan McDannold, David D. Liu et al.
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Stereotactic and Functional Neurosurgery
Neurological disorders and treatments
article

Magnetic Resonance Image-Guided Focused Ultrasound Ventral Intermediate Nucleus Thalamotomy with Indwelling Globus Pallidus Internus Deep Brain Stimulation Electrodes: A Case Report

G. Rees Cosgrove, Albert Y. Hung, Nathan McDannold, David D. Liu, Emily Ferenczi, Alexander P. Glaser, P. Jason White
article en

Abstract

This is the first report of MRgFUS thalamotomy for recurrent tremor with indwelling DBS electrodes. We found that MRgFUS thalamotomy as salvage therapy with implanted GPi DBS electrodes is both safe and effective. It represents a novel potential treatment paradigm for TdPD patients with persistent tremor despite otherwise effective GPi DBS.

Stereotactic and Functional NeurosurgeryVol. 103(4)
Brigham and Women's Hospital (US), Harvard University (US), Massachusetts General Hospital (US)
Good health and well-being
Openalex Percentile: Top 78%
Neurological disorders and treatments
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Magnetic Resonance Image-Guided Focused Ultrasound Ventral Intermediate Nucleus Thalamotomy with Indwelling Globus Pallidus Internus Deep Brain Stimulation Electrodes: A Case Report — G. Rees Cosgrove, Albert Y. Hung, et al. · Stereotactic and Functional Neurosurgery (2025) | TGRS Research Map | TGRS