Frequency and Clinical Outcomes Associated With Tau Positron Emission Tomography Positivity
In a large convenience sample, a positive tau PET scan occurred at a nonnegligible rate among cognitively unimpaired individuals, and the combination of Aβ PET positivity and tau PET positivity was associated with a high risk of clinical progression in both preclinical and symptomatic stages of AD. These findings underscore the potential of tau PET as a biomarker for staging AD pathology.
Authors
- Heidi I.L. Jacobs (ORCID: https://orcid.org/0000-0001-7620-3822)
- Donna Masterman
- Marie‐Élyse Lafaille‐Magnan
- Jennifer Tremblay‐Mercier (ORCID: https://orcid.org/0000-0001-5824-3740)
- Reisa Anne Sperling (ORCID: https://orcid.org/0000-0003-1535-6133)
- Alexandra Touroutoglou (ORCID: https://orcid.org/0000-0001-9679-2433)
- Pierre N. Tariot (ORCID: https://orcid.org/0000-0002-6058-8032)
- Ronald J. Thomas (ORCID: https://orcid.org/0000-0002-6041-9394)
- Gérard N. Bischof (ORCID: https://orcid.org/0000-0002-4366-5171)
- Paul A Yuschkevich
- Lawrence S. Honig (ORCID: https://orcid.org/0000-0002-9703-2265)
- Lea T. Grinberg (ORCID: https://orcid.org/0000-0002-6809-0618)
- Clément Debacker (ORCID: https://orcid.org/0000-0003-4887-7920)
- Charles DeCarli
- Serge Gauthier (ORCID: https://orcid.org/0000-0003-4272-3330)
- Kristi Wilmes
- Clifford R. Jack (ORCID: https://orcid.org/0000-0001-7916-622X)
- Pierre Orban (ORCID: https://orcid.org/0000-0003-3201-9614)
- Aaron P. Schultz (ORCID: https://orcid.org/0000-0002-0418-0999)
- Alejandro Costoya‐Sánchez (ORCID: https://orcid.org/0000-0002-5072-1282)
- Alireza Atri (ORCID: https://orcid.org/0000-0003-4405-6973)
- Payam Mahboubi
- Tharick Ali Pascoal (ORCID: https://orcid.org/0000-0001-9057-8014)
- Magdalena Korecka (ORCID: https://orcid.org/0000-0003-3129-8295)
- Jean‐Robert Maltais
- Deborah Blacker (ORCID: https://orcid.org/0000-0001-6107-7376)
- Michel J. Grothe (ORCID: https://orcid.org/0000-0003-2600-9022)
- Paule‐Joanne Toussaint (ORCID: https://orcid.org/0000-0002-7446-150X)
- Valle Camacho (ORCID: https://orcid.org/0000-0003-0748-0847)
- John Neuhaus (ORCID: https://orcid.org/0000-0003-0998-4352)
- Maura Malpetti (ORCID: https://orcid.org/0000-0001-8923-9656)
- Alexander Knaack (ORCID: https://orcid.org/0000-0002-5231-3637)
- Robert I. Reid (ORCID: https://orcid.org/0000-0003-2391-8650)
- Juliet Fockler
- David Maillet (ORCID: https://orcid.org/0000-0002-8545-062X)
- Duygu Tosun (ORCID: https://orcid.org/0000-0001-8644-7724)
- Shelley Moore
- Elizabeth Shaffer (ORCID: https://orcid.org/0000-0001-6017-1539)
- Jorge Sepulcre (ORCID: https://orcid.org/0000-0002-4199-2304)
- Pierre Étienne (ORCID: https://orcid.org/0000-0002-7275-9599)
- Nathalie Nilsson (ORCID: https://orcid.org/0000-0002-5236-3263)
- Richard J. Perrin (ORCID: https://orcid.org/0000-0002-3443-7716)
- Alan C. Evans (ORCID: https://orcid.org/0000-0003-3841-6098)
- Angelina J. Polsinelli (ORCID: https://orcid.org/0000-0002-7738-9574)
- Miranda Tuwaig
- Elisabeth Sylvain
- Renuka Giles
- Étienne Vachon‐Presseau (ORCID: https://orcid.org/0000-0002-8681-3154)
- John T. O’Brien (ORCID: https://orcid.org/0000-0002-0837-5080)
- Alexa Pichet Binette (ORCID: https://orcid.org/0000-0001-5218-3337)
- Vladimir Fonov (ORCID: https://orcid.org/0000-0003-3402-7749)
- Judes Poirier
- Nina Silverberg
- Arthur W. Toga (ORCID: https://orcid.org/0000-0001-7902-3755)
- Laura Mahar
- M. Mallar Chakravarty (ORCID: https://orcid.org/0000-0002-0759-5508)
- Guerda Duclair
- Renaud La Joie (ORCID: https://orcid.org/0000-0003-2581-8100)
- Sylvie Dubuc
- Yuna Gu (ORCID: https://orcid.org/0009-0007-3200-3977)
- Sophia I. Thomopoulos (ORCID: https://orcid.org/0000-0002-0046-4070)
- Ginette Mayrand
- Thomas Beaudry
- Gloria Leblond‐Baccichet
- Jamie Near (ORCID: https://orcid.org/0000-0003-3516-936X)
- Shannon L. Risacher (ORCID: https://orcid.org/0000-0002-3304-7943)
- Nick C. Fox (ORCID: https://orcid.org/0000-0002-6660-657X)
- Suzanne Craft (ORCID: https://orcid.org/0000-0003-0591-8657)
- Irina A. Skylar-Scott
- Neda Jahanshad (ORCID: https://orcid.org/0000-0003-4401-8950)
- Prokopis C. Prokopiou (ORCID: https://orcid.org/0000-0002-5444-8359)
- Alexander Taurone
- René Desautels
- Mélissa Savard
- Louise Hudon
- S. J. Wolk (ORCID: https://orcid.org/0000-0002-0826-9261)
- Béry Mohammediyan
- Karen Crawford (ORCID: https://orcid.org/0000-0002-3294-0828)
- Roos J. Jutten (ORCID: https://orcid.org/0000-0002-3712-4790)
- Jordana Remz
- Melissa McSweeney
- Rik Ossenkoppele (ORCID: https://orcid.org/0000-0003-1584-7477)
- John Q. Trojanowki
- James B. Rowe (ORCID: https://orcid.org/0000-0001-7216-8679)
- Alan N. Barkun (ORCID: https://orcid.org/0000-0002-1798-5526)
- Andrew J. Saykin (ORCID: https://orcid.org/0000-0002-1376-8532)
- David Fontaine
- Lisa L. Barnes (ORCID: https://orcid.org/0000-0002-0072-9817)
- Jihwan Yun
- Erin Franklin (ORCID: https://orcid.org/0000-0002-6614-4109)
- Marie Bernard (ORCID: https://orcid.org/0000-0003-3807-8009)
- Pablo Aguiar (ORCID: https://orcid.org/0000-0002-7322-2195)
- Joseph C. Masdeu (ORCID: https://orcid.org/0000-0001-9955-6954)
- Chester A. Mathis (ORCID: https://orcid.org/0000-0001-9811-0950)
- Wagner S. Brum (ORCID: https://orcid.org/0000-0002-9777-0559)
- Erik S. Musiek (ORCID: https://orcid.org/0000-0002-8873-0360)
- Arvin Forghanian-Arani
- Michael Donohue (ORCID: https://orcid.org/0000-0001-6026-2238)
- Tom Montine
- Rachel F. Buckley (ORCID: https://orcid.org/0000-0002-5356-5537)
- Maiya R. Geddes (ORCID: https://orcid.org/0009-0000-2371-934X)
- Ian Grant (ORCID: https://orcid.org/0000-0001-6960-6762)
- Erin Householder
- A. Claudio Cuello (ORCID: https://orcid.org/0000-0003-2143-2745)
- Leopoldina Carmo
- Theresa Köbe (ORCID: https://orcid.org/0000-0002-5438-6899)
- Yuliana Cabrera
- Stéphanie Tullo (ORCID: https://orcid.org/0000-0003-4608-3000)
- Liana G. Apostolova (ORCID: https://orcid.org/0000-0003-1823-2451)
- Morteza Pishnamazi
- Holly Newbold‐Fox
- Cristina Lois Gómez
- Frédéric St‐Onge (ORCID: https://orcid.org/0000-0002-5609-5729)
- Stephanie R Chen
- Andrés Perissinotti (ORCID: https://orcid.org/0000-0003-4190-2425)
- Jean‐Paul Soucy (ORCID: https://orcid.org/0000-0001-6979-1259)
- John Hsiao (ORCID: https://orcid.org/0000-0003-3471-7539)
- Marianne Chapleau (ORCID: https://orcid.org/0000-0001-8917-2594)
- Sander C.J. Verfaillie (ORCID: https://orcid.org/0000-0003-1820-3378)
- Josée Frappier
- Yasser Ituria‐Medina
- Emma M. Coomans (ORCID: https://orcid.org/0000-0002-4289-9101)
- Edmarie Guzmán‐Vélez (ORCID: https://orcid.org/0000-0002-3076-0727)
- Valentina Garibotto (ORCID: https://orcid.org/0000-0003-2422-698X)
- Danielle Harvey
- Christine Tardif (ORCID: https://orcid.org/0000-0001-8356-6808)
- Justin Kat
- Marianne Dufour
- Melissa Appleby (ORCID: https://orcid.org/0000-0002-4012-2438)
- Jeremy Pizzola
- Elsmarieke van de Giessen
- Tanya Lee
- Erik C. B. Johnson (ORCID: https://orcid.org/0000-0002-0604-2944)
- Karen Wan
- Ruben Smith (ORCID: https://orcid.org/0000-0001-7147-0112)
- Godfrey Coker
- Sulantha Mathotaarachchi (ORCID: https://orcid.org/0000-0001-9391-4503)
- Jeffrey L. Dage (ORCID: https://orcid.org/0000-0002-2192-1699)
- Prashanthi Vemuri (ORCID: https://orcid.org/0000-0003-4286-0589)
- Michal Figurski
- Stephanie A. Schultz (ORCID: https://orcid.org/0000-0001-8460-4415)
- Hazal Ozlen (ORCID: https://orcid.org/0000-0001-9715-6252)
- Sarah Walter (ORCID: https://orcid.org/0009-0003-3222-3102)
- Brad C. Dickerson
- Jennifer R. Gatchel (ORCID: https://orcid.org/0000-0002-3892-9742)
- Chiadi U. Onyike (ORCID: https://orcid.org/0000-0003-2255-4437)
- Sandhitsu R. Das (ORCID: https://orcid.org/0000-0003-0530-2887)
- Eric M. Reiman (ORCID: https://orcid.org/0000-0002-0705-3696)
- Bernardino Ghetti (ORCID: https://orcid.org/0000-0002-1842-8019)
- Mark Choe
- Fatiha Benbouhoud
- Oskar Hansson (ORCID: https://orcid.org/0000-0001-8467-7286)
- Claude Lepage
- Justin Miron (ORCID: https://orcid.org/0000-0002-9671-7449)
- Marie‐Josee Élie
- Guylaine Gagné
- Matthew L. Senjem (ORCID: https://orcid.org/0000-0001-9308-9275)
- Haley Bernhardt
- Gustavo Jimenez‐Maggiora (ORCID: https://orcid.org/0000-0001-9745-5121)
- Mahsa Dadar (ORCID: https://orcid.org/0000-0003-4008-2672)
- Caileigh Zimmerman
- Gil Dan Rabinovici (ORCID: https://orcid.org/0000-0002-3626-4265)
- Blandine Courcot
- Taylor Clanton
- Rick Hoge
- Bret Borowski
- Derek Flenniken
- Joel Kramer
- Yakeel T. Quiroz (ORCID: https://orcid.org/0000-0001-9714-8244)
- Dustin B. Hammers (ORCID: https://orcid.org/0000-0002-1644-2618)
- Gad A. Marshall (ORCID: https://orcid.org/0000-0002-9096-2355)
- Mirela Petkova
- Adam Fleisher (ORCID: https://orcid.org/0000-0002-2556-0878)
- Gretchen Reynolds (ORCID: https://orcid.org/0000-0003-4838-5096)
- Jens C. Pruessner (ORCID: https://orcid.org/0000-0002-8582-2980)
- Patrizia Vannini (ORCID: https://orcid.org/0000-0002-9425-1059)
- Kyle Womack (ORCID: https://orcid.org/0000-0002-6060-9075)
- John C.S. Breitner (ORCID: https://orcid.org/0000-0003-4229-4687)
- Véronique Pagé
- Christina Kazazian
- Laurel Beckett (ORCID: https://orcid.org/0000-0002-2418-9843)
- Sharon J. Sha (ORCID: https://orcid.org/0000-0002-3666-1463)
- Emily Rogalskı (ORCID: https://orcid.org/0000-0002-6472-1363)
- Christopher G. Schwarz (ORCID: https://orcid.org/0000-0002-1466-8357)
- Alyssa Salaciak (ORCID: https://orcid.org/0000-0003-0977-6289)
- Seqian Wang
- Pamela LaMontagne (ORCID: https://orcid.org/0000-0002-6752-8518)
- Walter A. Kukull (ORCID: https://orcid.org/0000-0001-8761-9014)
- Chengshi Jin (ORCID: https://orcid.org/0000-0002-6431-790X)
- Nancy J. Donovan (ORCID: https://orcid.org/0000-0002-6328-1589)
- Natasha Rajah
- Anne Labonté (ORCID: https://orcid.org/0000-0001-8076-7540)
- Hyun‐Sik Yang (ORCID: https://orcid.org/0000-0002-8318-0443)
- Olusegun Adegoke
- Vinod Venugopalan
- Kate Oaoo
- D. Louis Collins (ORCID: https://orcid.org/0000-0002-8432-7021)
- David N. Soleimani‐Meigooni (ORCID: https://orcid.org/0000-0003-4197-3039)
- Cynthia Picard (ORCID: https://orcid.org/0000-0003-1107-6839)
- Fiona Heeman
- Michael J. Pontecorvo (ORCID: https://orcid.org/0000-0002-8419-7589)
- David Thomas Jones (ORCID: https://orcid.org/0000-0002-4807-9833)
- John C. Morris (ORCID: https://orcid.org/0000-0001-9820-5618)
- Kathy L. Newell (ORCID: https://orcid.org/0000-0002-1648-7357)
- Fabiola Ferdinand
- Doris Dea
- Louise Théroux
- Débora Elisa Peretti (ORCID: https://orcid.org/0000-0002-3033-8817)
- Sophie Boutin (ORCID: https://orcid.org/0009-0007-6640-5114)
- Ismini Mainta (ORCID: https://orcid.org/0000-0001-5296-0116)
- Thomas J. Montine (ORCID: https://orcid.org/0000-0002-1346-2728)
- Rema Raman (ORCID: https://orcid.org/0000-0002-4096-6390)
- Federica Ribaldi (ORCID: https://orcid.org/0000-0001-9208-4472)
- William Z. Potter (ORCID: https://orcid.org/0000-0003-2529-6568)
- Angela Tam (ORCID: https://orcid.org/0000-0001-6752-5707)
- Christophe Bedetti (ORCID: https://orcid.org/0000-0002-1443-8922)
- Kelly Nudelman (ORCID: https://orcid.org/0000-0003-4040-1717)
- Gabriel Jean
- Nigel J. Cairns (ORCID: https://orcid.org/0000-0001-9858-3344)
- Mark J. Eisenberg (ORCID: https://orcid.org/0000-0002-1296-0661)
- Rana El‐Khoury
- Jason Brandt (ORCID: https://orcid.org/0000-0001-7381-6244)
- Julie Bailly
- Ian B. Malone (ORCID: https://orcid.org/0000-0001-7512-7856)
- Alexis Moscoso (ORCID: https://orcid.org/0000-0003-0170-036X)
- Bellec Pierre
- Geoffroy Gagliardi (ORCID: https://orcid.org/0000-0002-2608-8456)
- Héctor Alfredo Baptista González (ORCID: https://orcid.org/0000-0003-0340-0942)
- Eliezer Masliah (ORCID: https://orcid.org/0000-0002-2117-5569)
- Michael Schöll (ORCID: https://orcid.org/0000-0001-7800-1781)
- Talia M. Nir (ORCID: https://orcid.org/0000-0002-7106-7443)
- Mariam Ashford
- Enmanuelle Pardilla‐Delgado (ORCID: https://orcid.org/0000-0003-1149-3157)
- Cat Conti
- R. Nathan Spreng (ORCID: https://orcid.org/0000-0003-1530-8916)
- Sarah Farzin (ORCID: https://orcid.org/0000-0002-4222-6935)
- Joanne Frenette
- Eduard Teigner
- Alexander Drzezga (ORCID: https://orcid.org/0000-0001-6018-716X)
- Clara Vila‐Castelar (ORCID: https://orcid.org/0000-0002-8779-1487)
- Lindsey Hergesheimer
- Rachel L. Nosheny (ORCID: https://orcid.org/0000-0003-4995-8319)
- Martijn van Essen (ORCID: https://orcid.org/0000-0002-2257-1651)
- Christian Dansereau (ORCID: https://orcid.org/0000-0003-3363-1901)
- Mario F. Mendez (ORCID: https://orcid.org/0000-0001-6441-7989)
- Ani Eloyan (ORCID: https://orcid.org/0000-0002-8110-7680)
- Sang Won Seo (ORCID: https://orcid.org/0000-0002-8747-0122)
- Isabelle Vallée (ORCID: https://orcid.org/0000-0002-0395-3048)
- Valérie Gervais
- Illana Leppert
- Sylvia Villeneuve (ORCID: https://orcid.org/0000-0003-2338-0467)
- Galina Pogossova
- Robert A. Koeppe (ORCID: https://orcid.org/0000-0002-9514-5311)
- Adrienne Kormos
- Eunice Farah Saint‐Fort
- Paul Thompson (ORCID: https://orcid.org/0009-0009-5319-739X)
- Omar Darío Rodríguez-Fonseca
- Cécile Madjar (ORCID: https://orcid.org/0000-0003-1108-031X)
- Jeannie‐Marie Leoutsakos (ORCID: https://orcid.org/0000-0002-1010-1046)
- Rebecca England Amariglio (ORCID: https://orcid.org/0009-0009-5878-8930)
- Véronique D. Bohbot
- Julie Gonneaud (ORCID: https://orcid.org/0000-0003-0566-5581)
- Jacob W. Vogel (ORCID: https://orcid.org/0000-0001-6394-9940)
- Elena Anthal
- Ranjan Duara (ORCID: https://orcid.org/0000-0001-8060-6309)
- Renee Gordon
- Susan Landau (ORCID: https://orcid.org/0000-0003-4826-6134)
- Gerhard Multhaup
- Bradford Clark Dickerson (ORCID: https://orcid.org/0000-0002-5958-3445)
- Kwangsik Nho
- Zaven S. Khachaturian
- Raymond Scott Turner (ORCID: https://orcid.org/0000-0001-7534-2935)
- Jesús Silva‐Rodríguez (ORCID: https://orcid.org/0000-0002-5196-0103)
- Jasmeer P. Chhatwal (ORCID: https://orcid.org/0000-0002-7792-1698)
- Marina Dauar‐Tedeschi
- Shirin Tabrizi (ORCID: https://orcid.org/0000-0002-7984-5043)
- Keith A. Johnson (ORCID: https://orcid.org/0000-0002-5916-6043)
- Dallas P. Veitch (ORCID: https://orcid.org/0000-0002-9918-0640)
- Pedro Rosa‐Neto (ORCID: https://orcid.org/0000-0001-9116-1376)
- Kewei Chen (ORCID: https://orcid.org/0000-0001-8497-3069)
- Li Shen (ORCID: https://orcid.org/0000-0002-5443-0503)
- Doris Couture
- David Clark (ORCID: https://orcid.org/0000-0002-8882-9205)
- Leslie M. Shaw (ORCID: https://orcid.org/0000-0002-7650-1210)
- Stephanie Smith (ORCID: https://orcid.org/0000-0002-2543-2606)
- Yalin Chen (ORCID: https://orcid.org/0000-0002-4265-1018)
- Samir Das
- Axel Mathieu
- Michael Walter Weiner (ORCID: https://orcid.org/0000-0002-0144-1954)
- Thomas S. Wingo (ORCID: https://orcid.org/0000-0002-7679-6282)
- Claudia Greco
- Jonathan Jackson
- Laurie Ryan
- Michelle E. Farrell
- Charles Edouard Carrier
- Diane Michaud
- Dorene M. Rentz
- Marı́a C. Carrillo
- Kelley Faber (ORCID: https://orcid.org/0000-0003-3224-2736)
- Neill R Graff-Radford
- Mark A. Sager
- Tatiana M. Foroud
- Ronald C. Petersen
- William Jagust
- Carole Ho (ORCID: https://orcid.org/0000-0003-4250-092X)
- Giovanni B. Frisoni (ORCID: https://orcid.org/0000-0001-7075-7082)
- Simon Ducharme (ORCID: https://orcid.org/0000-0002-7309-1113)
- David S. Knopman
- Paul Aisen
- Devon Gessert
- Evan Fletcher
- Sheelakumari Raghavan
- Kala Kirby
- Scott Neu
- Steven Salloway
- Leon J. Thal
- Pierre Rioux
- Vasavan Nair
- Garrett Miller
- Penelope Kostopoulos
- Leslie‐Ann Daoust
- Michael Rafii
- Julie Price
- Jennifer Salazar
- Elsa Yu
- Lisa Taylor‐Reinwald
- Chad Ward
- P.T. Meyer
- Melissa E. Murray
- Jeff Gunter
- Robert C Green
- Maryanne Thangarajah
- Anne‐Marie Faubert
- Kejal Kantarci
- Laksanun Cheewakriengkrai
- Meghan Riddle
- Gregory S Day
- Julien Legarde
Institutions
- University of Geneva (CH)
- Universitat Autònoma de Barcelona (ES)
- Alzheimer's Association (US)
- Brigham and Women's Hospital (US)
- Universidade Federal do Rio Grande do Sul (BR)
- San Francisco VA Medical Center (US)
- Mayo Clinic (US)
- Harvard University (US)
- Lawrence Berkeley National Laboratory (US)
- Eli Lilly (United States) (US)
- Forschungszentrum Jülich (DE)
- University of California, San Francisco (US)
- Lund University (SE)
- MRC Cognition and Brain Sciences Unit (GB)
- Universidade de Santiago de Compostela (ES)
- Washington University in St. Louis (US)
- Samsung (South Korea) (KR)
- University of Cambridge (GB)
- Douglas Mental Health University Institute (CA)
- Sahlgrenska University Hospital (SE)
- Instituto de Salud Carlos III (ES)
- German Center for Neurodegenerative Diseases (DE)
- Hospital de Sant Pau (ES)
- Samsung Medical Center (KR)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- Gordon Center for Medical Imaging (US)
- Massachusetts General Hospital (US)
- Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (ES)
- Alzheimer’s Disease Neuroimaging Initiative (US)
- University Hospital of Geneva (CH)
- Amsterdam Neuroscience (NL)
- Center for Research in Molecular Medicine and Chronic Diseases (ES)
- Centro de Investigación Biomédica en Red (ES)
- McGill Genome Centre (CA)
- UK Dementia Research Institute (GB)
- Centre d'Imagerie BioMedicale (CH)
- Skåne University Hospital (SE)
- Hospital Universitario Lucus Augusti (ES)
- Instituto de Investigación Sanitaria de Santiago (ES)
- National Hospital for Neurology and Neurosurgery (GB)
- University Hospital Cologne (DE)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Indiana University School of Medicine
- University College London (GB)
- McGill University (CA)
- Indiana University – Purdue University Indianapolis (US)
- Sungkyunkwan University (KR)
- Vrije Universiteit Amsterdam (NL)
- University of Gothenburg (SE)
- Medical Research Council (GB)
- University of California, Berkeley (US)
Publication Details
- Journal
- JAMA
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1001/jama.2025.7817
- Citations
- 29
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 39.44
Funders
- U.S. Department of Defense
- U.S. Department of Veterans Affairs
- Alzheimer's Association
- Larry L. Hillblom Foundation
- Bristol-Myers Squibb
- Eli Lilly and Company
- Pfizer
- California Department of Public Health
- Brigham and Women's Hospital
- Massachusetts General Hospital
- Biogen
- University of Southern California
- Washington University in St. Louis
- Cleveland Clinic
- Alzheimer's Disease Neuroimaging Initiative
- BioClinica
- McGill University
- Faculty of Medicine, McGill University
- Demensförbundet
- ACADIA Pharmaceuticals
- Alexander Family Foundation
- Prothena
- GHR Foundation
- Apellis Pharmaceuticals
- Government of Canada
- National Institute for Health and Care Research
- University of Cambridge
- University College London
- University of Oxford
- European Commission
- Australian Catholic University
- National Research Foundation
- Deutsche Forschungsgemeinschaft
- Sungkyunkwan University
- Cambridge University Hospitals
- Lunds Universitet
- Korea Health Industry Development Institute
- National Research Foundation of Korea
- Eisai
- Knut och Alice Wallenbergs Stiftelse
- Novo Nordisk
- Vetenskapsrådet
- Taipei Medical University
- Deutsches Zentrum für Neurodegenerative Erkrankungen
- Sahlgrenska Universitetssjukhuset
- Göteborgs Universitet
- National Center for Geriatrics and Gerontology
- Universität zu Köln
- Skånes universitetssjukhus
- Ministry of Science and ICT, South Korea
- UK Dementia Research Institute
- National Institutes of Health
- Genentech
- Samsung
- University of California, San Francisco
- School of Medicine, Indiana University
- Pfizer Canada
- Avid Radiopharmaceuticals
- HORIZON EUROPE Framework Programme
- Charles F. and Joanne Knight Alzheimer Disease Research Center, Washington University in St. Louis
- Medical Research Council
- Korea National Institute of Health
- Sahlgrenska Akademin
- Institute for Information and Communications Technology Promotion
- Wallenberg Centre for Molecular and Translational Medicine
- National Institute on Aging
- Department of Radiology and Biomedical Imaging, University of California, San Francisco
- Lawrence Berkeley National Laboratory