Tipping Point Analysis
This JAMA Guide to Statistics and Methods explains tipping point analysis, which assesses how a range of hypothetical patterns in missing outcome data in a randomized clinical trial (RCT) would affect the study’s conclusions, and examines its use in an RCT of treatment for hypertension.
Authors
- Kehua Zhou (ORCID: https://orcid.org/0000-0002-2844-1604)
- Kendra D. Sims (ORCID: https://orcid.org/0000-0002-6740-3002)
- Yan Liu (ORCID: https://orcid.org/0000-0002-6433-0151)
Institutions
- Boston University (US)
- Beijing University of Chinese Medicine (CN)
- University of California, San Francisco (US)
- University of Colorado Anschutz Medical Campus (US)
Publication Details
- Journal
- JAMA
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1001/jama.2025.7420
- Citations
- 6
- Primary Topic
- Health Systems, Economic Evaluations, Quality of Life
- Type
- article
- Field-Weighted Citation Impact
- 18.79