Oscillation in the SIRS model

We study the SIRS epidemic model, both analytically and on a square lattice. The analytic model has two stable solutions, post outbreak/epidemic (no infected, I=0) and the endemic state (constant number of infected: I>0). When the model is implemented with noise, or on a lattice, a third state is possible, featuring regular oscillations. This is understood as a cycle of boom and bust, where an epidemic sweeps through, and dies out leaving a small number of isolated infecteds. As immunity wanes, herd immunity is lost throughout the population and the epidemic repeats. The key result is that the oscillation is an intrinsic feature of the system itself, not driven by external factors such as seasonality or behavioural changes. The model shows that non-seasonal oscillations, such as those observed for the omicron COVID variant, need no additional explanation such as the appearance of more infectious variants at regular intervals or coupling to behaviour. We infer that the loss of immunity to the SARS-CoV-2 virus occurs on a timescale of about ten weeks.

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Publication Details

Journal
Journal of Theoretical Biology
Published
2025-06-16
DOI
https://doi.org/10.1016/j.jtbi.2025.112169
Citations
1
Primary Topic
COVID-19 epidemiological studies
Type
article
Field-Weighted Citation Impact
1.37

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article

Oscillation in the SIRS model

Davide Marenduzzo, Aidan T. Brown, Graeme J. Ackland, Craig W. Miller
1 citations
Journal of Theoretical Biology
COVID-19 epidemiological studies
1.37
article

Oscillation in the SIRS model

Davide Marenduzzo, Aidan T. Brown, Graeme J. Ackland, Craig W. Miller
article en
1 citations

Abstract

We study the SIRS epidemic model, both analytically and on a square lattice. The analytic model has two stable solutions, post outbreak/epidemic (no infected, I=0) and the endemic state (constant number of infected: I>0). When the model is implemented with noise, or on a lattice, a third state is possible, featuring regular oscillations. This is understood as a cycle of boom and bust, where an epidemic sweeps through, and dies out leaving a small number of isolated infecteds. As immunity wanes, herd immunity is lost throughout the population and the epidemic repeats. The key result is that the oscillation is an intrinsic feature of the system itself, not driven by external factors such as seasonality or behavioural changes. The model shows that non-seasonal oscillations, such as those observed for the omicron COVID variant, need no additional explanation such as the appearance of more infectious variants at regular intervals or coupling to behaviour. We infer that the loss of immunity to the SARS-CoV-2 virus occurs on a timescale of about ten weeks.

Journal of Theoretical BiologyVol. 611
University of Edinburgh (GB)
UK Research and Innovation, Engineering and Physical Sciences Research Council
Good health and well-being
Openalex Percentile: Top 20%
COVID-19 epidemiological studies
1.37
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