Dingzhen pills inhibit neuronal ferroptosis and neuroinflammation by inhibiting the cGAS-STING pathway for Parkinson’s disease mice
This study is helpful to understand the molecular mechanism of the multi-component, multi-target neuroprotective effect of DZ, and may contribute to the development of DZP as a new therapeutic strategy for clinical application in PD.
Authors
- Guang-Xin Yue
- Shaoyu Luo (ORCID: https://orcid.org/0009-0000-3396-4517)
- Yuqin Yang (ORCID: https://orcid.org/0000-0002-2751-5499)
- Tingyu Li (ORCID: https://orcid.org/0000-0002-1757-9106)
- Shuai Zhang (ORCID: https://orcid.org/0000-0003-4480-533X)
- Ting Li (ORCID: https://orcid.org/0000-0002-8408-2482)
- Xin Xue (ORCID: https://orcid.org/0000-0002-7781-1982)
- Yu‐Kun Zhao (ORCID: https://orcid.org/0009-0002-3615-037X)
- Lei Tong (ORCID: https://orcid.org/0000-0003-2626-4162)
- Gaoshuang Fu
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1186/s13020-025-01135-9
- Citations
- 1
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- National Natural Science Foundation of China