Spectral CT imaging for assessment of metastases in melanoma patients: multi-reader evaluation

We found that in melanoma patients, the benefit of dlDECT-derived spectral reconstructions depends on the assessed tissue. While assessment of skeletal muscle and peritoneal metastases was significantly improved, low or absent iodine uptake of subcutaneous lesions led to false negatives and a consecutive decrease in sensitivity.

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Publication Details

Journal
Cancer Imaging
Published
2025-06-16
DOI
https://doi.org/10.1186/s40644-025-00889-7
Citations
2
Primary Topic
Advanced X-ray and CT Imaging
Type
article
Field-Weighted Citation Impact
1.35

Funders

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article

Spectral CT imaging for assessment of metastases in melanoma patients: multi-reader evaluation

Nils Große Hokamp, Philip Rauen, Thorsten Persigehl, Nicole Kreuzberg et al.
2 citations
Cancer Imaging
Advanced X-ray and CT Imaging
1.35
article

Spectral CT imaging for assessment of metastases in melanoma patients: multi-reader evaluation

Nils Große Hokamp, Philip Rauen, Thorsten Persigehl, Nicole Kreuzberg, Carola Heneweer, Christian Nelles, Simon Lennartz, Mathilda Weisthoff, Thomas Dratsch, David Zopfs, Hasan Zaytoun, Jonathan Kottlors, David Maintz, Pascale Bernard, Franziska Meyer, Anja Dobrostal, Pia Lena Niederau
article en
2 citations

Abstract

We found that in melanoma patients, the benefit of dlDECT-derived spectral reconstructions depends on the assessed tissue. While assessment of skeletal muscle and peritoneal metastases was significantly improved, low or absent iodine uptake of subcutaneous lesions led to false negatives and a consecutive decrease in sensitivity.

Cancer ImagingVol. 25(1)
University of Cologne (DE), University Hospital Cologne (DE)
Universitätsklinikum Köln
Affordable and clean energy
Openalex Percentile: Top 19%
Advanced X-ray and CT Imaging
1.35
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