Pd, Rh-Catalyzed Regioselective Hydroformylation of Olefins with Formic Acid and Its Salts
Efficient Pd- or Rh-catalyzed regioselective hydroformylation processes with HCO<sub>2</sub>Na/Ac<sub>2</sub>O or HCO<sub>2</sub>H/Ac<sub>2</sub>O are described. The linear aldehydes can be obtained in good yields with high l/b ratios. These two systems (HCO<sub>2</sub>Na/Ac<sub>2</sub>O vs HCO<sub>2</sub>H/Ac<sub>2</sub>O) give generally comparable results with their own advantages for certain substrates. In general, the Pd-catalyzed formylation reaction gives higher regioselectivities for vinyl arenes, while the Rh-catalyzed process gives higher regioselectivities for certain alkyl terminal olefins. All of these formylation processes are simple to operate and provide complementary methods for the synthesis of aldehydes from olefins.
Authors
- Wenlong Ren (ORCID: https://orcid.org/0000-0002-2028-4667)
- Yian Shi (ORCID: https://orcid.org/0000-0001-9016-2078)
- Jinzi Huang
- Yang Liu (ORCID: https://orcid.org/0000-0002-6859-0161)
- Xujian Sheng
- Jintao Ou
Institutions
- Catalytic Materials (United States) (US)
- Changzhou University (CN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1021/acs.joc.5c00597
- Citations
- 2
- Primary Topic
- Carbon dioxide utilization in catalysis
- Type
- article
- Field-Weighted Citation Impact
- 1.41