Integrated multi-omics and machine learning reveals immune-metabolic signatures in osteoarthritis: from bulk RNA-seq to single-cell resolution
Our findings indicate that immune metabolism plays a key role in the development of OA and provide new perspectives for future therapeutic strategies.
Authors
- Shijian Zhao (ORCID: https://orcid.org/0000-0002-2052-5600)
- Hui He
- Yinteng Wu
- Xiumei Zhao (ORCID: https://orcid.org/0000-0001-7555-4305)
- Bo Zhang (ORCID: https://orcid.org/0000-0002-7167-4083)
Institutions
- Guangxi Medical University (CN)
- Kunming Medical University (CN)
- First Affiliated Hospital of GuangXi Medical University (CN)
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-16
- DOI
- https://doi.org/10.3389/fimmu.2025.1599930
- Citations
- 5
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 8.34