Exploring T-cell metabolism in tuberculosis: development of a diagnostic model using metabolic genes
Our findings reveal that TCM-DEGs critically regulate TB progression through immune-metabolic reprogramming and cell-cell communication networks. The developed diagnostic model and molecular subtyping strategy enable precise TB-LTBI differentiation and inform immunotherapy optimization.
Authors
- Jinghua Gao (ORCID: https://orcid.org/0000-0001-8714-3028)
- Yuyang Zhou (ORCID: https://orcid.org/0009-0006-1344-7524)
- Chunxiao Huang (ORCID: https://orcid.org/0000-0001-6109-1135)
- Changlong Bi (ORCID: https://orcid.org/0000-0002-3621-6685)
- Zihan Cai
- Shoupeng Ding
Institutions
- Yang Hospital (KR)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1186/s40001-025-02768-0
- Citations
- 3
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 2.39