Alpha-CGRP as a specific response mediator during acute myocardial infarction in humans: findings from an observational longitudinal study
Alpha-CGRP is acutely elevated during AMI, likely as a compensatory vasodilator response to ischemia. Its post-AMI normalization suggests a transient protective mechanism. Further research is needed to explore its role in AMI-related pathophysiology and usefulness as a therapeutic agent.
Authors
- Gorka Garate (ORCID: https://orcid.org/0000-0001-9285-8810)
- Juan Manuel de Jesús Cortés de la Torre
- Julio Pascual (ORCID: https://orcid.org/0000-0002-3189-7573)
- Vicente González‐Quintanilla (ORCID: https://orcid.org/0000-0003-0902-3906)
- Marcos Sanmartín (ORCID: https://orcid.org/0009-0005-9972-4010)
- L. Gangas
Institutions
- Universidad de Cantabria (ES)
- Marqués de Valdecilla University Hospital (ES)
- Instituto de Investigación Marqués de Valdecilla (ES)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-06-16
- DOI
- https://doi.org/10.3389/fcvm.2025.1581056
- Primary Topic
- Neuropeptides and Animal Physiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Instituto de Salud Carlos III
- Agencia Estatal de Investigación