Genetic markers of enhanced functional antibody responses to COVID-19 vaccination
Primary COVID-19 vaccination induced increased S2-specific IgG in G1m1,17<sup>+/+</sup> vaccinees, facilitating enhanced anti-viral FcγR engagement and suggesting immunogenetics may be a valuble consideration for next-generation vaccine design.
Authors
- P. Mark Hogarth (ORCID: https://orcid.org/0000-0002-0360-7890)
- Adam K. Wheatley (ORCID: https://orcid.org/0000-0002-5593-9387)
- Katherine Kedzierska (ORCID: https://orcid.org/0000-0001-6141-335X)
- Thi H. O. Nguyen (ORCID: https://orcid.org/0000-0002-9294-7693)
- Siddhartha Mahanty (ORCID: https://orcid.org/0000-0003-1068-0524)
- Deborah Anne Williamson (ORCID: https://orcid.org/0000-0001-7363-6665)
- Katherine A. Bond (ORCID: https://orcid.org/0000-0002-4473-9232)
- Jason A. Trubiano (ORCID: https://orcid.org/0000-0002-5111-6367)
- Kevin J. Selva (ORCID: https://orcid.org/0000-0002-0780-9422)
- Janine M. Trevillyan (ORCID: https://orcid.org/0000-0002-8660-5558)
- Jennifer A. Juno (ORCID: https://orcid.org/0000-0002-9072-1017)
- Stephen John Kent (ORCID: https://orcid.org/0000-0002-8539-4891)
- Bruce D. Wines (ORCID: https://orcid.org/0000-0002-4108-375X)
- Kanta Subbarao (ORCID: https://orcid.org/0000-0003-1713-3056)
- Amy W. Chung (ORCID: https://orcid.org/0000-0003-0020-9704)
- Ruth A Purcell (ORCID: https://orcid.org/0000-0001-6378-5114)
- L. Carissa Aurelia
- Lilith F. Allen (ORCID: https://orcid.org/0000-0002-4197-2573)
Institutions
- Burnet Institute (AU)
- The University of Melbourne (AU)
- Peter MacCallum Cancer Centre (AU)
- Melbourne Sexual Health Centre (AU)
- Peter Doherty Institute (AU)
Publication Details
- Journal
- Vaccine
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1016/j.vaccine.2025.127379
- Citations
- 1
- Primary Topic
- SARS-CoV-2 and COVID-19 Research
- Type
- article
- Field-Weighted Citation Impact
- 1.40