Low-fibre diet is associated with high-risk coronary plaque features
A low-fibre diet with high red meat content was associated with high-risk plaques features, increased coronary calcification and significant stenosis. Waist circumference, TGs, and hypertension emerged as potential mediators of these associations, underscoring the role of metabolic and hemodynamic factors in the dietary impact on coronary atherosclerosis. Our findings strengthen the importance of cardioprotective dietary recommendations.
Authors
- Henrik Hagström
- Göran M.L. Bergström (ORCID: https://orcid.org/0000-0003-4289-5722)
- Emily Sonestedt (ORCID: https://orcid.org/0000-0002-0747-4562)
- Ulf Risérus (ORCID: https://orcid.org/0000-0002-8620-4586)
- Mats Ryberg (ORCID: https://orcid.org/0000-0003-3851-1132)
- Maria Wennberg (ORCID: https://orcid.org/0000-0002-1673-8494)
- Carl‐Johan Carlhäll (ORCID: https://orcid.org/0000-0003-2198-9690)
- Tomas Jernberg (ORCID: https://orcid.org/0000-0003-1695-379X)
- Tanja Kero (ORCID: https://orcid.org/0009-0008-2002-8699)
- Jiangming Sun (ORCID: https://orcid.org/0000-0001-6814-1297)
- Mats Eriksson (ORCID: https://orcid.org/0000-0001-6481-5549)
- Isabel Gonçalves (ORCID: https://orcid.org/0000-0002-2935-0181)
- Annika Rosengren (ORCID: https://orcid.org/0000-0002-5409-6605)
- Caroline Schmidt (ORCID: https://orcid.org/0000-0001-8534-3237)
- Isabel Drake (ORCID: https://orcid.org/0000-0002-6500-6310)
- Carl Johan Östgren (ORCID: https://orcid.org/0000-0003-1617-3179)
- Jan Engvall (ORCID: https://orcid.org/0000-0002-5716-5098)
- Krister Lindmark (ORCID: https://orcid.org/0000-0002-5756-7791)
- Marju Orho‐Melander (ORCID: https://orcid.org/0000-0002-3578-2503)
- Kerstin Cederlund (ORCID: https://orcid.org/0000-0001-8084-8260)
- Araz Rawshani (ORCID: https://orcid.org/0000-0003-2066-3533)
- Ingrid Larsson (ORCID: https://orcid.org/0000-0003-3670-0861)
- Maria Mannila (ORCID: https://orcid.org/0000-0001-6189-2901)
- Shafqat Ahmad (ORCID: https://orcid.org/0000-0002-1914-5248)
Institutions
- Linköping University (SE)
- Uppsala University (SE)
- Brigham and Women's Hospital (US)
- Södertörn University (SE)
- Karolinska University Hospital (SE)
- Uppsala University Hospital (SE)
- Harvard University (US)
- Malmö University (SE)
- Lund University (SE)
- Science for Life Laboratory (SE)
- Sahlgrenska University Hospital (SE)
- Karolinska Institutet (SE)
- Skåne University Hospital (SE)
- University of Gothenburg (SE)
- Umeå University (SE)
Publication Details
- Journal
- Cardiovascular Research
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1093/cvr/cvaf088
- Citations
- 3
- Primary Topic
- Cardiovascular Disease and Adiposity
- Type
- article
- Field-Weighted Citation Impact
- 4.16
Funders
- University Hospitals
- Fondation Leducq
- Stiftelsen för Strategisk Forskning
- VINNOVA
- Svenska Forskningsrådet Formas
- Lunds Universitet
- Hjärt-Lungfonden
- Linköpings Universitet
- Karolinska Institutet
- Knut och Alice Wallenbergs Stiftelse
- Stockholms Läns Landsting
- Vetenskapsrådet
- Umeå Universitet
- Sahlgrenska Universitetssjukhuset
- Göteborgs Universitet
- Uppsala Universitet
- STROKE-Riksförbundet
- Skånes universitetssjukhus
- Stiftelsen för Strategisk Forskning