Giant Leydig Cell Tumor Presenting as Gynecomastia: A Rare Case Report and Review

This case report describes a 67-year-old man who presented with bilateral gynecomastia and a left palpable testicular mass of 10-years, no clinical signs of hypogonadism. Hormonal evaluation found a low level of testosterone. Upon orchiectomy via an inguinal approach, a giant Leydig cell tumor of 15 cm in diameter was removed. The patient recovered favorably with a rapid reduction in breast tension without a change in the size of the gynecomastia. There was no recurrence at 8-month follow-up. This tumor was notable for its size and it’s compressing effect causing a gynecomastia by a reduced secretion of Testosterone. In addition, in our case we described the state-of-art management of this rare tumor.

Authors

Publication Details

Journal
SAS Journal of Medicine
Published
2025-05-26
DOI
https://doi.org/10.36347/sasjm.2025.v11i05.037
Primary Topic
Testicular diseases and treatments
Type
article
Field-Weighted Citation Impact
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article

Giant Leydig Cell Tumor Presenting as Gynecomastia: A Rare Case Report and Review

Omar Jendouzi, A. El Idrissi Lamghari, Tbouda Mohamed, Abainou El Houssaine et al.
SAS Journal of Medicine
Testicular diseases and treatments
article

Giant Leydig Cell Tumor Presenting as Gynecomastia: A Rare Case Report and Review

Omar Jendouzi, A. El Idrissi Lamghari, Tbouda Mohamed, Abainou El Houssaine, Ali Halouache
article en

Abstract

This case report describes a 67-year-old man who presented with bilateral gynecomastia and a left palpable testicular mass of 10-years, no clinical signs of hypogonadism. Hormonal evaluation found a low level of testosterone. Upon orchiectomy via an inguinal approach, a giant Leydig cell tumor of 15 cm in diameter was removed. The patient recovered favorably with a rapid reduction in breast tension without a change in the size of the gynecomastia. There was no recurrence at 8-month follow-up. This tumor was notable for its size and it’s compressing effect causing a gynecomastia by a reduced secretion of Testosterone. In addition, in our case we described the state-of-art management of this rare tumor.

SAS Journal of MedicineVol. 11(05)
Openalex Percentile: Top 76%
Testicular diseases and treatments
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