Phenotype-Preserving Co-culture of Osteoblasts and Chondrocytes Enhances Bone-Cartilage Interface Integration in a PRP-Augmented Scaffold
This study demonstrates the feasibility of developing transplantable scaffolds containing co-cultured osteoblasts and chondrocytes while preserving their phenotypes. These scaffolds exhibit significant potential in promoting healing at the bone-cartilage interface, with PRP further enhancing proliferation and improving the scaffold's ability to promote bone-cartilage interface healing.
Authors
- Jeong Joon Yoo (ORCID: https://orcid.org/0000-0002-6304-0101)
- Jinwoo Nam
- Sunhyung Lee (ORCID: https://orcid.org/0000-0003-2814-6346)
- Hong Seok Kim (ORCID: https://orcid.org/0000-0001-7533-8979)
Institutions
- Seoul National University (KR)
- New Generation University College (ET)
- Seoul National University Hospital (KR)
- SNUH SMG-SNU Boramae Medical Center (KR)
- National University College (PR)
Publication Details
- Journal
- Tissue Engineering and Regenerative Medicine
- Published
- 2025-06-16
- DOI
- https://doi.org/10.1007/s13770-025-00727-8
- Citations
- 2
- Primary Topic
- Periodontal Regeneration and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.67
Funders
- National Research Foundation
- Seoul National University
- National Research Foundation of Korea
- Seoul National University Hospital
- Ministry of Science and ICT, South Korea