Association of triglyceride glucose index with incident diabetes among individuals with normal fasting triglycerides and fasting plasma glucose values: a general population-based retrospective cohort study
This large-scale study demonstrates a robust independent association between the TyG index and diabetes risk in individuals with normal FPG and TG levels. Our findings suggest that a TyG index exceeding 8.41 correlates with a progressively higher risk of diabetes development. These results collectively suggest the TyG index could serve as a clinically relevant predictor of diabetes incidence in this population.
Authors
- Yongchao Wang
- Tie Zhang (ORCID: https://orcid.org/0000-0003-3488-605X)
- Han Ma (ORCID: https://orcid.org/0000-0001-9985-3035)
- Rubing Guo (ORCID: https://orcid.org/0009-0006-5812-354X)
- Tiantian Cheng (ORCID: https://orcid.org/0000-0002-3734-0290)
- Wei Guang Zhao (ORCID: https://orcid.org/0000-0002-7887-2357)
Institutions
- China-Japan Friendship Hospital (CN)
- Gansu University of Traditional Chinese Medicine (CN)
- Beijing Chaoyang Emergency Medical Center (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-06-16
- DOI
- https://doi.org/10.3389/fendo.2025.1598171
- Citations
- 9
- Primary Topic
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Type
- article
- Field-Weighted Citation Impact
- 11.65
Funders
- Wu Jieping Medical Foundation