ScRNA-seq combined with ATAC-seq analysis to explore the metabolic balance mechanism of CCl4-induced liver inflammatory injury
Our findings contribute to the understanding of the evolution and underlying CCl4-induced inflammatory mechanisms governing hepatocyte inflammatory injury and the subsequent metabolic shift from imbalance toward balance under chronic CCl4 exposure, offering novel perspectives and directions for targeted therapeutic interventions in DILI.
Authors
- Hui Liu (ORCID: https://orcid.org/0000-0002-9340-7701)
- Shoubin Ning (ORCID: https://orcid.org/0000-0001-6066-0519)
Institutions
- United States Air Force (US)
- Air Force General Hospital PLA (CN)
- Shandong Provincial QianFoShan Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-16
- DOI
- https://doi.org/10.3389/fimmu.2025.1600685
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00