Transcriptional fingerprinting of regulatory T cells: ensuring quality in cell therapy applications
This Treg fingerprinting method provides a powerful tool to molecularly characterize Treg products, potentially enabling correlative analysis with the safety and efficacy outcomes of Treg-based cell therapies.
Authors
- Joshua Beilke
- Yuchi Honaker (ORCID: https://orcid.org/0000-0001-7183-4916)
- Yuanyuan Xiao (ORCID: https://orcid.org/0000-0003-2441-7209)
- Victor Yuan (ORCID: https://orcid.org/0000-0002-3394-998X)
- Joseph R. Arron (ORCID: https://orcid.org/0000-0001-7677-9979)
- S. Alice Long (ORCID: https://orcid.org/0000-0002-0281-1240)
- Steven A. Cincotta (ORCID: https://orcid.org/0000-0003-3802-3673)
- Lijie Wang (ORCID: https://orcid.org/0000-0001-8674-3128)
- Zhang Cheng
- J A Bluestone
- Christopher J. Page
- Sydney Vollhardt
Institutions
- Atara Biotherapeutics (United States) (US)
- Benaroya Research Institute
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-16
- DOI
- https://doi.org/10.3389/fimmu.2025.1602172
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00