Hydroalcoholic extract of Plumeria Acuminata's impact on wound healing in Wister Albino rats

Wound healing is a dynamic and complex process that involves inflammation, proliferation, and tissue remodeling. Natural plant extracts have been explored for their potential in accelerating wound repair due to their phytochemical richness. This study evaluates the wound healing efficacy of hydroalcoholic extract of Plumeria acuminata in Wistar albino rats using incision and excision wound models. Results indicated significant wound contraction, reduced epithelialization period, and enhanced tensile strength in extract-treated groups compared to the control. Histopathological analysis confirmed increased fibroblast activity, collagen deposition, and epithelial regeneration. The findings support the potential of P. acuminata as a promising natural wound healing agent.

Authors

Publication Details

Journal
International Journal of Pharmacology and Clinical Research
Published
2025-01-01
DOI
https://doi.org/10.33545/26647613.2025.v7.i1c.72
Primary Topic
Essential Oils and Antimicrobial Activity
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Hydroalcoholic extract of Plumeria Acuminata's impact on wound healing in Wister Albino rats

K.P. BHARGAVA, Rajesh Asija, Amandeep Swami
International Journal of Pharmacology and Clinical Research
Essential Oils and Antimicrobial Activity
article

Hydroalcoholic extract of Plumeria Acuminata's impact on wound healing in Wister Albino rats

K.P. BHARGAVA, Rajesh Asija, Amandeep Swami
article en

Abstract

Wound healing is a dynamic and complex process that involves inflammation, proliferation, and tissue remodeling. Natural plant extracts have been explored for their potential in accelerating wound repair due to their phytochemical richness. This study evaluates the wound healing efficacy of hydroalcoholic extract of Plumeria acuminata in Wistar albino rats using incision and excision wound models. Results indicated significant wound contraction, reduced epithelialization period, and enhanced tensile strength in extract-treated groups compared to the control. Histopathological analysis confirmed increased fibroblast activity, collagen deposition, and epithelial regeneration. The findings support the potential of P. acuminata as a promising natural wound healing agent.

International Journal of Pharmacology and Clinical ResearchVol. 7(1)
Zero hunger
Openalex Percentile: Top 84%
Essential Oils and Antimicrobial Activity
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.