POSTOPERATIVE PAIN RELIEF FOLLOWING INGUINAL HERNIOPLASTY: A RANDOMIZED CONTROLLED TRIAL COMPARING INTRAVENOUS KETOROLAC AND TRAMADOL

Background: Postoperative pain management is critical for recovery following inguinal hernioplasty. Tramadol, a commonly used opioid analgesic, is associated with side effects such as nausea, vomiting, and delayed bowel function. Ketorolac, a non-steroidal anti-inflammatory drug (NSAID), offers a potential alternative with fewer adverse effects. This study aimed to compare the analgesic efficacy and safety of intravenous ketorolac versus tramadol in patients undergoing elective open inguinal hernioplasty. Methods: In this prospective, randomized, double-blinded trial, 60 adult patients undergoing elective open inguinal hernioplasty under spinal anaesthesia were assigned to two groups: Group K received ketorolac 30 mg IV every 8 hours, and Group T received tramadol 50 mg IV every 8 hours. Pain was assessed using the Visual Analog Scale (VAS) at 2, 6, 12, and 24 hours postoperatively. Secondary outcomes included time to rescue analgesia, ambulation, and first flatus. Results: The ketorolac group had significantly lower VAS scores at all time points (p < 0.05), required less rescue analgesia, and showed faster recovery, with earlier ambulation and bowel function return. Postoperative Hemodynamic stability was maintained in both groups. Conclusion: Intravenous ketorolac provides superior analgesia and enhanced recovery compared to tramadol, making it an effective opioid-sparing option for postoperative pain management in inguinal hernioplasty. Key words: Inguinal hernioplasty, ketorolac, tramadol, randomized controlled trial, Visual Analog Scale, recovery outcomes.

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Publication Details

Journal
International Journal of Advanced Research
Published
2025-05-31
DOI
https://doi.org/10.21474/ijar01/20970
Primary Topic
Anesthesia and Pain Management
Type
article
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article

POSTOPERATIVE PAIN RELIEF FOLLOWING INGUINAL HERNIOPLASTY: A RANDOMIZED CONTROLLED TRIAL COMPARING INTRAVENOUS KETOROLAC AND TRAMADOL

Prashant Bhatia, Amit Sehgal, Saurabh Wadhwa, Abhishek Kumar Misra
International Journal of Advanced Research
Anesthesia and Pain Management
article

POSTOPERATIVE PAIN RELIEF FOLLOWING INGUINAL HERNIOPLASTY: A RANDOMIZED CONTROLLED TRIAL COMPARING INTRAVENOUS KETOROLAC AND TRAMADOL

Prashant Bhatia, Amit Sehgal, Saurabh Wadhwa, Abhishek Kumar Misra
article en

Abstract

Background: Postoperative pain management is critical for recovery following inguinal hernioplasty. Tramadol, a commonly used opioid analgesic, is associated with side effects such as nausea, vomiting, and delayed bowel function. Ketorolac, a non-steroidal anti-inflammatory drug (NSAID), offers a potential alternative with fewer adverse effects. This study aimed to compare the analgesic efficacy and safety of intravenous ketorolac versus tramadol in patients undergoing elective open inguinal hernioplasty. Methods: In this prospective, randomized, double-blinded trial, 60 adult patients undergoing elective open inguinal hernioplasty under spinal anaesthesia were assigned to two groups: Group K received ketorolac 30 mg IV every 8 hours, and Group T received tramadol 50 mg IV every 8 hours. Pain was assessed using the Visual Analog Scale (VAS) at 2, 6, 12, and 24 hours postoperatively. Secondary outcomes included time to rescue analgesia, ambulation, and first flatus. Results: The ketorolac group had significantly lower VAS scores at all time points (p < 0.05), required less rescue analgesia, and showed faster recovery, with earlier ambulation and bowel function return. Postoperative Hemodynamic stability was maintained in both groups. Conclusion: Intravenous ketorolac provides superior analgesia and enhanced recovery compared to tramadol, making it an effective opioid-sparing option for postoperative pain management in inguinal hernioplasty. Key words: Inguinal hernioplasty, ketorolac, tramadol, randomized controlled trial, Visual Analog Scale, recovery outcomes.

International Journal of Advanced ResearchVol. 13(05)
Openalex Percentile: Top 76%
Anesthesia and Pain Management
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