REBOUND HYPERTENSION AFTER CLONIDINE WITHDRAWAL IN A PEDIATRIC INTENSIVE CARE UNIT : A CASE REPORT

Clonidine abrupt cessation may cause a rebound hypertension. Diagnosis can be confirmed with clinical findings and an increase in noradrenaline urinary levels. We present the case of a patient who presented hypertension and tachycardia after clonidine withdrawal, with no increase in noradrenaline urinary levels, but with an increase in urinary dopamine levels, which is normally not increased significantly. We successfully treated hypertension with the reintroduction and progressive weaning of clonidine, after a therapeutic test with a dopamine antagonist. All catecholamines should be tested in the event of suspected rebound hypertension after clonidine withdrawal.

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Publication Details

Journal
International Journal of Advanced Research
Published
2025-05-31
DOI
https://doi.org/10.21474/ijar01/20969
Primary Topic
Renal function and acid-base balance
Type
article
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article

REBOUND HYPERTENSION AFTER CLONIDINE WITHDRAWAL IN A PEDIATRIC INTENSIVE CARE UNIT : A CASE REPORT

Idriss Chajai, Aziza Bentalha, S. Kettani, Zakaria El Hernoussi
International Journal of Advanced Research
Renal function and acid-base balance
article

REBOUND HYPERTENSION AFTER CLONIDINE WITHDRAWAL IN A PEDIATRIC INTENSIVE CARE UNIT : A CASE REPORT

Idriss Chajai, Aziza Bentalha, S. Kettani, Zakaria El Hernoussi
article en

Abstract

Clonidine abrupt cessation may cause a rebound hypertension. Diagnosis can be confirmed with clinical findings and an increase in noradrenaline urinary levels. We present the case of a patient who presented hypertension and tachycardia after clonidine withdrawal, with no increase in noradrenaline urinary levels, but with an increase in urinary dopamine levels, which is normally not increased significantly. We successfully treated hypertension with the reintroduction and progressive weaning of clonidine, after a therapeutic test with a dopamine antagonist. All catecholamines should be tested in the event of suspected rebound hypertension after clonidine withdrawal.

International Journal of Advanced ResearchVol. 13(05)
Openalex Percentile: Top 84%
Renal function and acid-base balance
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