[Dynamic distribution and clearance of <sup>99m</sup>Tc-DTPA in brain extracellular space].
Intracerebral ECS administration is a promising method of administration, but there are significant differences in distribution and clearance in different brain regions. This study further expands the content and significance of "ECS regions", and also provides an important theoretical foundation for the treatment of encephalopathy and the research of new drugs through brain ECS in the future.
Authors
- Zhaoheng Xie (ORCID: https://orcid.org/0000-0001-8003-8778)
- Yuan Liu (ORCID: https://orcid.org/0000-0002-1156-7673)
- Pengpeng Lv (ORCID: https://orcid.org/0000-0002-1863-4701)
- Yüan Cheng (ORCID: https://orcid.org/0000-0002-1153-9699)
- Jingjing Zou (ORCID: https://orcid.org/0000-0002-4749-105X)
- Zhilei Xu (ORCID: https://orcid.org/0000-0001-5112-2567)
- Hong Han (ORCID: https://orcid.org/0000-0001-8977-9679)
- Y Wang
- Mingzhe Liu (ORCID: https://orcid.org/0000-0001-7054-997X)
- David Liu (ORCID: https://orcid.org/0000-0003-0346-5033)
- Tian Gao (ORCID: https://orcid.org/0000-0002-2485-5439)
- Ming-Xun Ren (ORCID: https://orcid.org/0000-0002-4677-3290)
- Richard J. Long
Institutions
- Peking University (CN)
- Peking University First Hospital (CN)
- Peking University Third Hospital (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-06-18
- Primary Topic
- Radiopharmaceutical Chemistry and Applications
- Type
- article