Snake venom: An emerging anticancer agent

Snake venom consists of different proteins, enzymes, carbohydrates and other bioactive molecules. They are highly toxic in nature and have been recognized for their lethal effects for a long back. However recent studies have revealed the enormous therapeutic potential of snake venom. The crude venom and its enzymatic components including PLA2, SVMP, SVSP, Lectin, LAAO and disintegrin, exhibit anticancer activity through cell lysis, gene expression modulation, cytotoxicity and apoptosis. This review discusses the anticancer properties of various components of snake venom. Although venom isolation, purification and safety concerns are a challenge, ongoing research shows that snake venom holds great promise for the development of innovative and effective anticancer treatments, requiring further research and clinical trials to combat this disease.

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Publication Details

Journal
Research Journal of Biotechnology
Published
2025-05-31
DOI
https://doi.org/10.25303/207rjbt2120221
Primary Topic
Venomous Animal Envenomation and Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Snake venom: An emerging anticancer agent

Ayushi Gupta, Sandeep Kumar Jhade, Rahul Shrivastava
Research Journal of Biotechnology
Venomous Animal Envenomation and Studies
article

Snake venom: An emerging anticancer agent

Ayushi Gupta, Sandeep Kumar Jhade, Rahul Shrivastava
article en

Abstract

Snake venom consists of different proteins, enzymes, carbohydrates and other bioactive molecules. They are highly toxic in nature and have been recognized for their lethal effects for a long back. However recent studies have revealed the enormous therapeutic potential of snake venom. The crude venom and its enzymatic components including PLA2, SVMP, SVSP, Lectin, LAAO and disintegrin, exhibit anticancer activity through cell lysis, gene expression modulation, cytotoxicity and apoptosis. This review discusses the anticancer properties of various components of snake venom. Although venom isolation, purification and safety concerns are a challenge, ongoing research shows that snake venom holds great promise for the development of innovative and effective anticancer treatments, requiring further research and clinical trials to combat this disease.

Research Journal of BiotechnologyVol. 20(7)
Openalex Percentile: Top 84%
Venomous Animal Envenomation and Studies
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Snake venom: An emerging anticancer agent — Ayushi Gupta, Sandeep Kumar Jhade, et al. · Research Journal of Biotechnology (2025) | TGRS Research Map | TGRS