Pulmonary arterial hypertension in systemic lupus erythematosus: identification of risk factors and haemodynamics characteristics in a multicentre retrospective cohort
Our data showed that LAC+, RNP+, RP and a scleroderma pattern at NVC was indicative for patients with SLE-PAH. Our results pointed to generalised microvascular involvement and a hypercoagulation state in patients with SLE-PAH. The variables we identified could be used to implement a screening algorithm to identify patients with SLE at risk of developing PAH.
Authors
- Alessandra Bortoluzzi (ORCID: https://orcid.org/0000-0003-2416-8134)
- Micaela Fredi (ORCID: https://orcid.org/0000-0002-6511-4936)
- Lorenzo Cavagna (ORCID: https://orcid.org/0000-0003-3292-1528)
- Oliver Sander (ORCID: https://orcid.org/0000-0001-5196-9370)
- Matthieu Canuet (ORCID: https://orcid.org/0000-0002-8089-4846)
- Matthias Schneider (ORCID: https://orcid.org/0000-0002-7867-4430)
- Carlomaurizio Montecucco (ORCID: https://orcid.org/0000-0001-8263-3925)
- Franco Franceschini (ORCID: https://orcid.org/0000-0003-3678-6124)
- Emiliano Marasco (ORCID: https://orcid.org/0000-0001-5346-3357)
- Marianne Riou (ORCID: https://orcid.org/0000-0001-6807-8582)
- Christina Düsing (ORCID: https://orcid.org/0009-0005-2601-8203)
- Alain Meyer (ORCID: https://orcid.org/0000-0003-0893-6041)
- Rebecca S. B. Fischer (ORCID: https://orcid.org/0000-0002-5048-2955)
- Gamal Chehab (ORCID: https://orcid.org/0000-0001-7309-2370)
- Konstantinos Triantafyllias (ORCID: https://orcid.org/0000-0001-8764-2636)
- Andreas Schwarting (ORCID: https://orcid.org/0000-0002-0566-598X)
- Ilaria Cavazzana (ORCID: https://orcid.org/0000-0002-2757-7120)
- Claudia Bracaglia (ORCID: https://orcid.org/0000-0002-9834-9619)
- Jutta Richter (ORCID: https://orcid.org/0000-0001-8194-3243)
- Veronica Codullo (ORCID: https://orcid.org/0000-0003-2557-8514)
- Stefano Ghio (ORCID: https://orcid.org/0000-0002-1858-1152)
- Giovanni Zanframundo (ORCID: https://orcid.org/0000-0001-5042-1282)
- Ettore Silvagni (ORCID: https://orcid.org/0000-0001-7654-8222)
- Carlo Alberto Scirè
- Lisa Keller
- Sezgin Sahin
- Stefanie Keymel
Institutions
- Johannes Gutenberg University Mainz (DE)
- University of Ferrara (IT)
- University of Pavia (IT)
- Düsseldorf University Hospital (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- Istanbul University-Cerrahpaşa (TR)
- Bambino Gesù Children's Hospital (IT)
- Hôpitaux Universitaires de Strasbourg (FR)
- Policlinico San Matteo Fondazione (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Acura Kliniken (DE)
- Heinrich Heine University Düsseldorf (DE)
- University of Milano-Bicocca (IT)
- Université de Strasbourg (FR)
- University of Brescia (IT)
Publication Details
- Journal
- Lupus Science & Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1136/lupus-2024-001471
- Citations
- 1
- Primary Topic
- Pulmonary Hypertension Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.52