Development of zinc partially-stabilized cement carrying growth factor and anti-inflammatory drug for vital pulp therapy

The novel ZnPSC cements functionalized with VEGF and aspirin demonstrated the superior handling properties, mechanical strength, biocompatibility, and enhanced regenerative potential, making it a promising candidate for the vital pulp therapy. Further, in vivo studies are warranted to validate its therapeutic efficacy and biosafety.

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Publication Details

Journal
Journal of Dental Sciences
Published
2025-06-12
DOI
https://doi.org/10.1016/j.jds.2025.05.029
Primary Topic
Endodontics and Root Canal Treatments
Type
article
Field-Weighted Citation Impact
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article

Development of zinc partially-stabilized cement carrying growth factor and anti-inflammatory drug for vital pulp therapy

Chun-Liang Yeh, Chih‐Chun Chang, Tsao‐Li Chuang, Chun‐Pin Lin
Journal of Dental Sciences
Endodontics and Root Canal Treatments
article

Development of zinc partially-stabilized cement carrying growth factor and anti-inflammatory drug for vital pulp therapy

Chun-Liang Yeh, Chih‐Chun Chang, Tsao‐Li Chuang, Chun‐Pin Lin
article en

Abstract

The novel ZnPSC cements functionalized with VEGF and aspirin demonstrated the superior handling properties, mechanical strength, biocompatibility, and enhanced regenerative potential, making it a promising candidate for the vital pulp therapy. Further, in vivo studies are warranted to validate its therapeutic efficacy and biosafety.

Journal of Dental SciencesVol. 20(4)
Kaohsiung Medical University (TW), National Taiwan University (TW), National Taiwan University Hospital (TW)
Zero hunger
Openalex Percentile: Top 82%
Endodontics and Root Canal Treatments
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