A Randomized, Double‐Blind, Placebo‐Controlled Trial of Abatacept for the Treatment of Relapsing, Nonsevere Granulomatosis With Polyangiitis
In patients with relapsing, nonsevere GPA, abatacept did not reduce the risk of relapse, severe worsening, or failure to achieve remission.
Authors
- Rula A. Hajj‐Ali (ORCID: https://orcid.org/0000-0001-6314-4827)
- Robert Spiera (ORCID: https://orcid.org/0000-0003-2911-6800)
- Ulrich Specks (ORCID: https://orcid.org/0000-0002-6559-1206)
- Carol A. Langford (ORCID: https://orcid.org/0000-0001-9498-321X)
- Carol A. McAlear (ORCID: https://orcid.org/0000-0002-0016-6866)
- Marcia Friedman (ORCID: https://orcid.org/0000-0001-6722-2159)
- Ora Gewurz‐Singer
- NADER A. KHALIDI (ORCID: https://orcid.org/0000-0002-8270-2617)
- Elaine Yacyshyn (ORCID: https://orcid.org/0000-0002-2753-2790)
- Rennie L. Rhee (ORCID: https://orcid.org/0000-0002-4907-0304)
- Kenneth J. Warrington (ORCID: https://orcid.org/0000-0001-7708-2487)
- Oliver Floßmann (ORCID: https://orcid.org/0000-0001-5976-3609)
- Cristina Burroughs (ORCID: https://orcid.org/0000-0002-0660-8127)
- David D Cuthbertson (ORCID: https://orcid.org/0000-0002-3785-9834)
- Curry L. Koening (ORCID: https://orcid.org/0000-0002-4494-7672)
- Peter Lanyon (ORCID: https://orcid.org/0000-0002-9855-6802)
- Larry W. Moreland (ORCID: https://orcid.org/0000-0003-4483-0359)
- Rachel Bronwen Jones (ORCID: https://orcid.org/0000-0003-4790-283X)
- David R.W. Jayne (ORCID: https://orcid.org/0000-0002-1712-0637)
- Christian Pagnoux (ORCID: https://orcid.org/0000-0001-6287-9549)
- Yih Chang Lin
- Lindsy J. Forbess
- Paul A. Monach (ORCID: https://orcid.org/0000-0003-4937-0515)
- Jeffrey P. Krischer (ORCID: https://orcid.org/0000-0003-4526-888X)
- Bernhard Hellmich (ORCID: https://orcid.org/0000-0002-8014-1801)
- Jason Michael Springer (ORCID: https://orcid.org/0000-0002-3903-6049)
- Natasha Dehghan
- Aurore Fifi‐Mah (ORCID: https://orcid.org/0000-0001-5417-9825)
- Eamonn Molloy
- Peter A. Merkel (ORCID: https://orcid.org/0000-0001-9284-7345)
Institutions
- Boston University (US)
- Hospital for Special Surgery (US)
- Cedars-Sinai Medical Center (US)
- Mount Sinai Hospital (CA)
- Cleveland Clinic (US)
- Mayo Clinic (US)
- Nottingham University Hospitals NHS Trust (GB)
- University of British Columbia (CA)
- University of Alberta (CA)
- Oregon Health & Science University (US)
- University of Calgary (CA)
- University of Pittsburgh (US)
- University of Toronto (CA)
- University of Utah (US)
- University of Cambridge (GB)
- University of South Florida (US)
- University of Michigan (US)
- Royal Berkshire Hospital (GB)
- Cambridge School (PT)
- Bridge University (SS)
- Michigan United (US)
- St. Vincent's University Hospital (IE)
- University of Kansas Medical Center (US)
- St. Paul's Hospital (CA)
- St. Joseph’s Healthcare Hamilton (CA)
- University of Pennsylvania (US)
- University of Tübingen (DE)
- McMaster University (CA)
Publication Details
- Journal
- Arthritis & Rheumatology
- Published
- 2025-06-12
- DOI
- https://doi.org/10.1002/art.43272
- Citations
- 7
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 10.63
Funders
- Bristol-Myers Squibb
- University of Pennsylvania
- Cleveland Clinic
- University of Pittsburgh
- University of South Florida
- McMaster University
- Rare Diseases Clinical Research Network
- University of Alberta
- University of Toronto
- National Center for Research Resources
- National Center for Advancing Translational Sciences