Virulence Factors and Genes Diagnosis Treatment and Antibiotic Resistance of Staphylococcus Aureus in Ocular Infections

Staphylococcus aureus is a major opportunistic pathogen implicated in various ocular infections. Its pathogenicity is largely due to a wide arsenal of virulence factors and antibiotic resistance genes. This study discusses the surface proteins, toxins, enzymes, adhesins, and biofilm formation contributing to its virulence. The paper also explores diagnostic approaches, current treatment options including antibiotic eye drops, and the global challenge of antimicrobial resistance. Special focus is placed on key resistance genes such as ermA, ermB, icaA, LukS, and mecA. Awareness and control of antibiotic misuse are crucial in mitigating resistance trends.

Authors

Publication Details

Journal
South Asian Research Journal of Pharmaceutical Sciences
Published
2025-05-22
DOI
https://doi.org/10.36346/sarjps.2025.v07i03.002
Primary Topic
Ocular Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Virulence Factors and Genes Diagnosis Treatment and Antibiotic Resistance of Staphylococcus Aureus in Ocular Infections

Manal A. Awad, Karar Ali Abdulkhuder
South Asian Research Journal of Pharmaceutical Sciences
Ocular Infections and Treatments
article

Virulence Factors and Genes Diagnosis Treatment and Antibiotic Resistance of Staphylococcus Aureus in Ocular Infections

Manal A. Awad, Karar Ali Abdulkhuder
article en

Abstract

Staphylococcus aureus is a major opportunistic pathogen implicated in various ocular infections. Its pathogenicity is largely due to a wide arsenal of virulence factors and antibiotic resistance genes. This study discusses the surface proteins, toxins, enzymes, adhesins, and biofilm formation contributing to its virulence. The paper also explores diagnostic approaches, current treatment options including antibiotic eye drops, and the global challenge of antimicrobial resistance. Special focus is placed on key resistance genes such as ermA, ermB, icaA, LukS, and mecA. Awareness and control of antibiotic misuse are crucial in mitigating resistance trends.

South Asian Research Journal of Pharmaceutical SciencesVol. 7(03)
Openalex Percentile: Top 78%
Ocular Infections and Treatments
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