Anti‐thymocyte globulin in immune‐mediated cytopenias: A monocentric experience and literature review

Anti-thymocyte globulin in multi-refractory immune-mediated cytopenia is an effective treatment, with response rate as high as 65%. Younger patients, presenting with thrombocytopenia or neutropenia, and those with LGL and STAT3 mutations appear to be more likely responsive.

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Publication Details

Journal
British Journal of Haematology
Published
2025-06-12
DOI
https://doi.org/10.1111/bjh.20165
Primary Topic
Blood disorders and treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Anti‐thymocyte globulin in immune‐mediated cytopenias: A monocentric experience and literature review

Luca Guarnera, Carlos Bravo‐Pérez, Matteo D’Addona, Christopher Haddad et al.
British Journal of Haematology
Blood disorders and treatments
article

Anti‐thymocyte globulin in immune‐mediated cytopenias: A monocentric experience and literature review

Luca Guarnera, Carlos Bravo‐Pérez, Matteo D’Addona, Christopher Haddad, Valeria Visconte, Arooj Ahmed, Olisaemeka Ogbue, Carmelo Gurnari, Arda Durmaz, Aashray Mandala, Serhan Ünlü, Jaroslaw Pawel Maciejewski, Zachary Brady
article en

Abstract

Anti-thymocyte globulin in multi-refractory immune-mediated cytopenia is an effective treatment, with response rate as high as 65%. Younger patients, presenting with thrombocytopenia or neutropenia, and those with LGL and STAT3 mutations appear to be more likely responsive.

British Journal of HaematologyVol. 207(1)
University of Rome Tor Vergata (IT), Cleveland Clinic (US), Instituto de Salud Carlos III (ES), Hospital General Universitario Morales Meseguer (ES), Centre for Biomedical Network Research on Rare Diseases (ES), Universidad de Murcia (ES)
Aplastic Anemia and MDS International Foundation, Edward P. Evans Foundation, Instituto de Salud Carlos III
Openalex Percentile: Top 84%
Blood disorders and treatments
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Anti‐thymocyte globulin in immune‐mediated cytopenias: A monocentric experience and literature review — Luca Guarnera, Carlos Bravo‐Pérez, et al. · British Journal of Haematology (2025) | TGRS Research Map | TGRS