Focal Nodular Hyperplasia (FNH)/FNH‐Like Lesions: An Important Potential Mimic of Relapsed Malignancy in Pediatric Cancer Patients
Focal nodular hyperplasia (FNH) is a rare benign lesion of the liver, which is becoming increasingly recognized in survivors of pediatric cancer. These lesions are under-reported, but do not require further investigation or treatment. We present two cases with unusual imaging findings consistent with an FNH/FNH-like process after completing intensive cancer treatment; both patients were managed without invasive investigation or treatment and remain clinically well. It is important to recognize FNH/FNH-like lesions in this cohort of patients and avoid unnecessary invasive investigation and management.
Authors
- Lauren Johansen (ORCID: https://orcid.org/0009-0001-0947-577X)
- Ben J. Fleming (ORCID: https://orcid.org/0000-0003-0111-8679)
- Matthew Jonathan Murray (ORCID: https://orcid.org/0000-0002-4480-1147)
- Jonathan Abrams (ORCID: https://orcid.org/0000-0002-4044-6969)
- C. Elizabeth Hook (ORCID: https://orcid.org/0000-0002-0450-7656)
Institutions
- University of Cambridge (GB)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- Birmingham Children's Hospital (GB)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2025-06-12
- DOI
- https://doi.org/10.1002/pbc.31851
- Citations
- 2
- Primary Topic
- Soft tissue tumor case studies
- Type
- article
- Field-Weighted Citation Impact
- 3.34