Research Progress on the Synthesis of Dibenzopyranone and Its Derivatives

二苯并吡喃酮及其衍生物是一类具有重要生物活性和应用价值的杂环化合物，广泛存在于天然产物(如黄酮类、香豆素类化合物)中，并展现出抗氧化、抗炎、抗菌及抗肿瘤等特性。近年来，其合成研究已成为有机领域的热点之一。本文系统综述了此类化合物在药物化学和材料科学中的应用潜力，以及合成策略与研究进展，重点讨论了传统合成路线和近年来发展的绿色合成方法。指出了当前合成领域中存在的挑战，并对未来研究方向进行了展望，为二苯并吡喃酮化合物的合成及应用研究提供参考。Dibenzopyranone and its derivatives are a class of heterocyclic compounds with important biological activity and application value, widely present in natural products such as flavonoids and coumarins, and exhibiting antioxidant, anti-inflammatory, antibacterial, and anti-tumor properties. In recent years, its synthesis research has become one of the hotspots in the organic field. This article systematically reviews the potential applications of such compounds in medicinal chemistry and materials science, as well as their synthesis strategies and research progress, with a focus on traditional synthesis routes and green synthesis methods developed in recent years. The challenges in the current synthesis field were pointed out, and future research directions were discussed, providing reference for the synthesis and application research of dibenzopyranone compounds.