Association of Increased Epstein–Barr Virus Reactivation With Imbalanced Immunity and Myenteric Neuron Loss in Achalasia
Although relatively low, our findings reveal an increased frequency of EBV reactivation in patients with achalasia, which may be associated with imbalanced immunity and neuron loss in LES in these subpopulations. This study provides novel insights into the role of EBV reactivation in achalasia.
Authors
- Zhao‐Chao Zhang (ORCID: https://orcid.org/0000-0003-1560-7107)
- Liyun Ma
- Ping‐Hong Zhou (ORCID: https://orcid.org/0000-0002-5434-0540)
- Zu‐Qiang Liu
- Lu Yao (ORCID: https://orcid.org/0000-0001-6164-7770)
- Jiaqi Xu (ORCID: https://orcid.org/0000-0002-2774-5016)
- Quan‐Lin Li (ORCID: https://orcid.org/0000-0002-9108-8786)
- Li Wang (ORCID: https://orcid.org/0000-0003-3379-2721)
- Yun Wang (ORCID: https://orcid.org/0000-0002-0369-9895)
- Xiaoqing Li (ORCID: https://orcid.org/0000-0003-1334-1544)
- Zihan Geng (ORCID: https://orcid.org/0000-0003-2690-3374)
- Kehao Wang (ORCID: https://orcid.org/0000-0001-5485-7091)
- Ling Du (ORCID: https://orcid.org/0000-0002-3019-4315)
- Wei‐Feng Chen
- Meng‐Jiang He
Institutions
- Fudan University (CN)
- Zhongshan Hospital of Xiamen University (CN)
- Zhongshan Hospital (CN)
- South China Institute of Collaborative Innovation (CN)
Publication Details
- Journal
- Journal of Gastroenterology and Hepatology
- Published
- 2025-06-12
- DOI
- https://doi.org/10.1111/jgh.17018
- Citations
- 2
- Primary Topic
- Eosinophilic Esophagitis
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Program of Shanghai Academic Research Leader