Baicalin alleviates sepsis-associated acute kidney injury through activation of the PPAR-γ/UCP1 signaling pathway
Baicalin protects against SA-AKI by activating the PPAR-γ/UCP1 signaling pathway. This study provides new insights into the mechanisms through which baicalin mitigates kidney injury in sepsis, suggesting its potential as a therapeutic agent for SA-AKI.
Authors
- Qiuju Huang (ORCID: https://orcid.org/0000-0001-7969-4903)
- Mingjia Gu (ORCID: https://orcid.org/0000-0001-9677-8279)
- Qingbo Lu (ORCID: https://orcid.org/0009-0005-6786-9100)
- Ya‐Fen Yu (ORCID: https://orcid.org/0000-0003-4432-2178)
- Xiang Yu (ORCID: https://orcid.org/0000-0001-5806-497X)
- Neng Bao (ORCID: https://orcid.org/0000-0002-6841-1311)
- Xuexue Zhu (ORCID: https://orcid.org/0000-0002-4735-5648)
- Hai‐Jian Sun (ORCID: https://orcid.org/0000-0002-7791-5335)
- Xin Gu
- Jin Wang (ORCID: https://orcid.org/0009-0002-4560-8231)
Institutions
- Jiangnan University (CN)
- Nanjing University of Chinese Medicine (CN)
- Wuxi Fourth People's Hospital (CN)
- Changshu No.1 People's Hospital (CN)
Publication Details
- Journal
- Renal Failure
- Published
- 2025-06-12
- DOI
- https://doi.org/10.1080/0886022x.2025.2508908
- Citations
- 2
- Primary Topic
- Heme Oxygenase-1 and Carbon Monoxide
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Jiangsu Province