An Overview on Floating Tablets
Pharmaceutical technology has advanced significantly with the advent of Novel Drug Delivery Systems (NDDS), especially in the area of creating novel and creative formulations intended to increase therapeutic efficacy. In addition to improving the stability, bioavailability, and general safety of pharmaceutical substances, these advanced NDDS play a crucial role in protecting them against several types of degradation that may take place during storage or after administration. Among the wide variety of NDDS floating tablets, there are special benefits and mechanisms catered to particular medical requirements. Additionally, the developed floating tablets show off their exceptional ability to stay afloat in the stomach contents, allowing for the regulated release of medications over a longer time frame. This ultimately improves therapeutic outcomes and gastric retention. The goal of this paper is to present a thorough analysis of floating tablets, covering their mechanism, preparation techniques, and assessment criteria. and conclusion. In order to achieve the best buoyancy and drug release kinetics, major formulation elements such polymer selection, gasgeneration agents, and tablet density are essential. Floating methods are divided into effervescent and non-effervescent systems. The advantages of these sophisticated systems include not just improved drug absorption but also a notable decrease in unfavorable side effects for specific drug classes. Researchers and pharmaceutical professionals looking to create novel and potent floating tablet formulations might use this review as a resource
Authors
- Rizwana Khan (ORCID: https://orcid.org/0000-0002-9210-9024)
- Twinkie Yadav Twinkie Yadav
- Bhawna Sharma Bhawna Sharma
- Priyanka Priyanka
Publication Details
- Journal
- International Journal of Pharmaceutical Research and Applications
- Published
- 2025-03-01
- DOI
- https://doi.org/10.35629/4494-1003530538
- Primary Topic
- Pharmaceutical studies and practices
- Type
- article
- Field-Weighted Citation Impact
- 0.00