Formulation and Evaluation of Transdermal Niosomal Patches of Doxorubicin for Breast Cancer

Here, we report the synthesis and Evaluation of Niosomes loaded transdermal patches it is effective means to deliver Doxorubicin to diagnosis cancer like breast cancer. Doxorubicin treats different type of cancer like, breast cancer, bladder cancer, Kaposi's sarcoma, lymphoma, and acute lymphocytic leukemia. Niosomes are the non-ionic surfactant vesicles obtained on hydration of synthetic non-ionic surfactants.These are the promising vehicles for effective transdermal drug delivery.Niosomesdo not cause any cardiotoxicity Soliposomal encapsulation of the doxorubicin limits cardiotoxicity. Pereparation of niosomesbased Doxorubicin Patches is gastroretentive drug delivery system.Reduce Side Effect with conventional formulations and increase penetration of drug and drug bioavaibility.