Strategies for Formulation and Evaluation of Poly Herbal Effervescent Granules for the Management of Digestive Activity’’

This research focused on formulating and evaluating effervescent granules of fennel (Foeniculum vulgare)seed Powder, known for its carminative, digestive, and antispasmodic properties. The goal was to enhance the palatability of herbal formulations by reducing bitterness while improving dissolution, ensuring a quicker onset of action. Citric acid, tartaric acid, sodium bicarbonate, and other excipients were incorporated using the wet granulation method to prepare effervescent granules.fennel seed powder was formulated into four different batches (F1-F4), and their flow properties, PH, and effervescence time were evaluated. The results indicated that granules exhibited excellent flow for all formulations remained within three minutes, with formulation F1 emerging as the most optimized due to its enhanced drug release (98.30%) and rapid effervescent time of approximately 95 second. The findings suggest that effervescent granules of fennel could serve as a promising formulation for improving herbal drug effectiveness and patient compliance

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Publication Details

Journal
International Journal of Pharmaceutical Research and Applications
Published
2025-03-01
DOI
https://doi.org/10.35629/4494-1003491494
Primary Topic
Polysaccharides Composition and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Strategies for Formulation and Evaluation of Poly Herbal Effervescent Granules for the Management of Digestive Activity’’

Katara Kinjalben Katara Kinjalben, Mr.Sunil Ohja Mr.Sunil Ohja
International Journal of Pharmaceutical Research and Applications
Polysaccharides Composition and Applications
article

Strategies for Formulation and Evaluation of Poly Herbal Effervescent Granules for the Management of Digestive Activity’’

Katara Kinjalben Katara Kinjalben, Mr.Sunil Ohja Mr.Sunil Ohja
article en

Abstract

This research focused on formulating and evaluating effervescent granules of fennel (Foeniculum vulgare)seed Powder, known for its carminative, digestive, and antispasmodic properties. The goal was to enhance the palatability of herbal formulations by reducing bitterness while improving dissolution, ensuring a quicker onset of action. Citric acid, tartaric acid, sodium bicarbonate, and other excipients were incorporated using the wet granulation method to prepare effervescent granules.fennel seed powder was formulated into four different batches (F1-F4), and their flow properties, PH, and effervescence time were evaluated. The results indicated that granules exhibited excellent flow for all formulations remained within three minutes, with formulation F1 emerging as the most optimized due to its enhanced drug release (98.30%) and rapid effervescent time of approximately 95 second. The findings suggest that effervescent granules of fennel could serve as a promising formulation for improving herbal drug effectiveness and patient compliance

International Journal of Pharmaceutical Research and ApplicationsVol. 10(3)
Klinik und Poliklinik für Psychosomatik und Psychotherapie (DE)
Openalex Percentile: Top 84%
Polysaccharides Composition and Applications
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