Three Distinct Pathways to First Episode Mania and Psychosis: Latent Class Analysis of Antecedent Psychopathology
This study identified three distinct pathways to FEM and FEP, offering a transdiagnostic perspective on the antecedent illness trajectories of BD and SZ. Future research should validate these categories that are more inclusive than the classic BD versus SZ dichotomy and explore their potential for predicting illness course and guiding personalized early interventions.
Authors
- Alessandro Miola (ORCID: https://orcid.org/0000-0002-2513-2718)
- Mark A. Frye (ORCID: https://orcid.org/0000-0001-6997-4215)
- Jennifer L. Vande Voort (ORCID: https://orcid.org/0000-0002-3630-4773)
- Javier Ortiz‐Orendain (ORCID: https://orcid.org/0000-0003-3983-1322)
- Alastair J. McKean (ORCID: https://orcid.org/0000-0002-0528-1134)
- Mete Ercis (ORCID: https://orcid.org/0000-0003-1272-5503)
- Vanessa Pazdernik (ORCID: https://orcid.org/0000-0001-7566-7334)
- Ayşegül Özerdem (ORCID: https://orcid.org/0000-0002-9455-5896)
- Manuel Gardea‐Resendez (ORCID: https://orcid.org/0000-0002-9825-8792)
- Peggy M. Gruhlke
- Ian Michel (ORCID: https://orcid.org/0000-0002-1014-3393)
- Tamahara Gonzalez‐Campos (ORCID: https://orcid.org/0000-0001-6342-0596)
Institutions
- Mayo Clinic (US)
- University of Padua (IT)
- Universidad Autónoma de Nuevo León (MX)
- University of New Mexico (US)
- WinnMed (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Acta Psychiatrica Scandinavica
- Published
- 2025-06-13
- DOI
- https://doi.org/10.1111/acps.13826
- Citations
- 1
- Primary Topic
- Schizophrenia research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- National Institute on Aging