Phytopharmaceutical Formulation of Adulsa Syrup: A Natural Remedy for Asthma

This research explores the development and evaluation of a herbal syrup formulated with Adhatoda vasica (commonly known as Adulsa), a medicinal plant traditionally used in the treatment of respiratory ailments, particularly asthma. The plant contains bioactive compounds such as vasicine and vasicinone, known for their bronchodilatory, expectorant, and anti-inflammatory effects. An aqueous extract of Adulsa leaves was used to prepare the syrup, along with appropriate excipients to ensure palatability, stability, and patient compliance. The formulation underwent comprehensive quality control assessments including pH, viscosity, microbial load, and phytochemical screening to ensure pharmaceutical standards were met. Pharmacological studies, both in vitro and in vivo, demonstrated that the syrup significantly improved respiratory function, reduced bronchial inflammation, and facilitated mucus clearance. The formulation was found to be physically and chemically stable over a 90-day accelerated stability study and exhibited no acute toxicity in preliminary safety evaluations. The results indicate that the Adulsa-based syrup is a promising phytopharmaceutical candidate for asthma management. It offers a natural, cost-effective, and well-tolerated alternative to conventional synthetic drugs. Further clinical trials are recommended to validate its efficacy and safety in human subjects and to support its potential integration into mainstream therapeutic practices for respiratory disorders.