Some mathematical models for flagellar activation mechanisms

This paper focuses on studying a model for dyneins, cytoskeletal motor proteins responsible for axonemal activity. The model is a coupled system of partial differential equations inspired by [F. Jülicher and J. Prost, Cooperative molecular motors, Phys. Rev. Lett. 75 (1995) 2618–2621; F. Jülicher and J. Prost, Molecular motors: From individual to collective behavior, Prog. Theor. Phys. Suppl. 130 (1998) 9–16] and incorporating two rows of molecular motors between microtubules filaments. Existence and uniqueness of a solution are proved, together with the presence of a supercritical Hopf bifurcation. Additionally, numerical simulations are provided to illustrate the theoretical results. A brief study on the generalization to [Formula: see text]-rows is also included.

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Publication Details

Journal
Mathematical Models and Methods in Applied Sciences
Published
2025-06-13
DOI
https://doi.org/10.1142/s0218202525500423
Citations
3
Primary Topic
stochastic dynamics and bifurcation
Type
article
Field-Weighted Citation Impact
3.97
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article

Some mathematical models for flagellar activation mechanisms

Jessie Levillain, Antonio DeSimone, Aline Lefebvre-Lepot, Irene Anello et al.
3 citations
Mathematical Models and Methods in Applied Sciences
stochastic dynamics and bifurcation
3.97
article

Some mathematical models for flagellar activation mechanisms

Jessie Levillain, Antonio DeSimone, Aline Lefebvre-Lepot, Irene Anello, François Alouges
article en
3 citations

Abstract

This paper focuses on studying a model for dyneins, cytoskeletal motor proteins responsible for axonemal activity. The model is a coupled system of partial differential equations inspired by [F. Jülicher and J. Prost, Cooperative molecular motors, Phys. Rev. Lett. 75 (1995) 2618–2621; F. Jülicher and J. Prost, Molecular motors: From individual to collective behavior, Prog. Theor. Phys. Suppl. 130 (1998) 9–16] and incorporating two rows of molecular motors between microtubules filaments. Existence and uniqueness of a solution are proved, together with the presence of a supercritical Hopf bifurcation. Additionally, numerical simulations are provided to illustrate the theoretical results. A brief study on the generalization to [Formula: see text]-rows is also included.

Mathematical Models and Methods in Applied SciencesVol. 35(11)
Centre National de la Recherche Scientifique (FR), Scuola Internazionale Superiore di Studi Avanzati (IT), Institut Universitaire de France (FR), Université Paris-Saclay (FR)
Openalex Percentile: Top 7%
stochastic dynamics and bifurcation
3.97
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Some mathematical models for flagellar activation mechanisms — Jessie Levillain, Antonio DeSimone, et al. · Mathematical Models and Methods in Applied Sciences (2025) | TGRS Research Map | TGRS