Comprehensive analysis of molecular markers linked to antimalarial drug resistance in Plasmodium falciparum in Northern, Northeastern and Eastern Uganda
This study reveal rising partial artemisinin resistance and widespread antifolate resistance surpassing WHO thresholds in Northern, Northeastern, and Eastern Uganda. Emerging super-resistant parasites pose a serious threat to malaria control, necessitating urgent enhanced surveillance and alternative treatment strategies.
Authors
- Peter Olupot‐Olupot (ORCID: https://orcid.org/0000-0002-5757-609X)
- Thomas Katairo (ORCID: https://orcid.org/0000-0002-2002-8911)
- Florence Alaroker
- Charles Benard Okalebo
- Isaac Sewanyana
- Samuel L. Nsobya (ORCID: https://orcid.org/0000-0003-4986-8823)
- Osamudiamen Paul
- William Okiror (ORCID: https://orcid.org/0000-0003-0870-2800)
- George Paasi (ORCID: https://orcid.org/0000-0001-6360-0589)
- Gilbert Gilibrays Ocen (ORCID: https://orcid.org/0000-0002-2204-291X)
- Stephen Legesi Pande
- Denis Amorut
- Jimmy Patrick Alunyo (ORCID: https://orcid.org/0000-0002-7897-7730)
- Alex Oula
- Stephen Tukwasibwe (ORCID: https://orcid.org/0000-0002-6469-6516)
- Alice Nakiyemba
- Emmaluel Ocen
- Susan Nabadda Ndidde
Institutions
- Soroti Hospital (UG)
- Mbale Hospital (UG)
- Busitema University (UG)
- Ministry of Health (UG)
- Moroto Hospital (UG)
- IAC (United States) (US)
Publication Details
- Journal
- Malaria Journal
- Published
- 2025-06-13
- DOI
- https://doi.org/10.1186/s12936-025-05439-x
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wellcome Trust
- Imperial College London
- European Commission
- Busitema University
- European and Developing Countries Clinical Trials Partnership