Combined hereditary spherocytosis and β-thalassaemia trait: A rare co-existence

Haemoglobinopathies, the most prevalent haemolytic disease in India, make up the majority of patients in most haematology outpatient clinics. The most prevalent hereditary haemolytic anaemia is beta-thalassaemia trait (βTT). It often remains undiagnosed as it has an asymptomatic clinical course. However, βTT needs be identified to provide genetic counselling to the affected families and to reduce the number of affected children born, which will lower their overall financial burden. Better screening methods for haemoglobinopathies have increased the detection of mixed haemolytic anaemia. We report a patient with combined βTT and hereditary spherocytosis.

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Journal
˜The œNational Medical Journal of India
Published
2025-06-13
DOI
https://doi.org/10.25259/nmji_165_2024
Primary Topic
Hemoglobinopathies and Related Disorders
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article
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article

Combined hereditary spherocytosis and β-thalassaemia trait: A rare co-existence

Shuchismita Shuchismita, Iffat Jamal, Vijayanand Choudhary
˜The œNational Medical Journal of India
Hemoglobinopathies and Related Disorders
article

Combined hereditary spherocytosis and β-thalassaemia trait: A rare co-existence

Shuchismita Shuchismita, Iffat Jamal, Vijayanand Choudhary
article en

Abstract

Haemoglobinopathies, the most prevalent haemolytic disease in India, make up the majority of patients in most haematology outpatient clinics. The most prevalent hereditary haemolytic anaemia is beta-thalassaemia trait (βTT). It often remains undiagnosed as it has an asymptomatic clinical course. However, βTT needs be identified to provide genetic counselling to the affected families and to reduce the number of affected children born, which will lower their overall financial burden. Better screening methods for haemoglobinopathies have increased the detection of mixed haemolytic anaemia. We report a patient with combined βTT and hereditary spherocytosis.

˜The œNational Medical Journal of IndiaVol. 38(2)
Indira Gandhi Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 81%
Hemoglobinopathies and Related Disorders
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Combined hereditary spherocytosis and β-thalassaemia trait: A rare co-existence — Shuchismita Shuchismita, Iffat Jamal, et al. · ˜The œNational Medical Journal of India (2025) | TGRS Research Map | TGRS