Integrating Drosophila and Vibrio fischeri models for toxicity evaluation: uncovering detoxification trends in psoralea Fructus-TCM formulations
A method for detecting the toxicity variation patterns of PF, ESP, and SSP can be established using <i>Drosophila</i> and <i>Vibrio fischeri</i>, and the mechanisms of toxic effects can be explored respectively through transcriptomics and virtual screening techniques.
Authors
- Yina Li (ORCID: https://orcid.org/0000-0002-5479-5174)
- Chengrong Xiao
- Fangyang Li
- Cheng Zhang (ORCID: https://orcid.org/0000-0003-3049-1587)
- Yuguang Wang (ORCID: https://orcid.org/0000-0003-2260-5652)
- Yue Gao (ORCID: https://orcid.org/0000-0001-8454-8230)
- Zhuo Shi
- Xianglin Tang
- Chunqi Yang
- Wanyun Dang
Institutions
- Guangdong Pharmaceutical University (CN)
- Chinese PLA General Hospital (CN)
- Beijing University of Technology (CN)
- Beijing Radiation Center (CN)
- Hebei University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-06-13
- DOI
- https://doi.org/10.3389/fphar.2025.1590929
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China