Cutaneous small vessel vasculitis following calcium-hydroxyapatite filler: A rare case report

This case report describes a 61-year-old female who developed cutaneous small vessel vasculitis following a calcium-hydroxyapatite-based filler injection. The patient presented with a generalized purpuric and petechial rash, along with arthralgia. A skin biopsy confirmed features consistent with cutaneous small vessel vasculitis. Treatment with a 6-week prednisone taper resulted in complete symptom resolution. This observation warrants further investigation into the potential role of dermal fillers in triggering inflammatory conditions like cutaneous small vessel vasculitis.

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Publication Details

Journal
SAGE Open Medical Case Reports
Published
2025-06-13
DOI
https://doi.org/10.1177/2050313x251341563
Primary Topic
Autoimmune and Inflammatory Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Cutaneous small vessel vasculitis following calcium-hydroxyapatite filler: A rare case report

Sheila Kashkari, Badia Issa‐Chergui, Arieh Gomolin, May Chergui et al.
SAGE Open Medical Case Reports
Autoimmune and Inflammatory Disorders
article

Cutaneous small vessel vasculitis following calcium-hydroxyapatite filler: A rare case report

Sheila Kashkari, Badia Issa‐Chergui, Arieh Gomolin, May Chergui, Lisa Iannatone, Ghassan Barnawi
article en

Abstract

This case report describes a 61-year-old female who developed cutaneous small vessel vasculitis following a calcium-hydroxyapatite-based filler injection. The patient presented with a generalized purpuric and petechial rash, along with arthralgia. A skin biopsy confirmed features consistent with cutaneous small vessel vasculitis. Treatment with a 6-week prednisone taper resulted in complete symptom resolution. This observation warrants further investigation into the potential role of dermal fillers in triggering inflammatory conditions like cutaneous small vessel vasculitis.

SAGE Open Medical Case ReportsVol. 13
McGill University (CA)
Openalex Percentile: Top 80%
Autoimmune and Inflammatory Disorders
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Cutaneous small vessel vasculitis following calcium-hydroxyapatite filler: A rare case report — Sheila Kashkari, Badia Issa‐Chergui, et al. · SAGE Open Medical Case Reports (2025) | TGRS Research Map | TGRS